- #1
Giuseppechimico
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- TL;DR Summary
- Need to prepare the following solution taken from a published study:
"1% povidone–iodine solution in a liquid vehicle system that included 44% USP-grade DMSO"
Hi everyone,
I am trying to make a solution described in a published study but I am not sure on how to interpret it correctly:
"We have been using a low-dose formulation of 1% Povidone-Iodine (w/w) in a solution containing dimethyl sulfoxide (DMSO)...
"1% povidone–iodine solution in a liquid vehicle system that included 44% USP-grade DMSO"Now I can easily find pure liquid DMSO but only a 100mL of 10% w/v Povidone-Iodine (PVP-I).
Based on my (limited..) understanding, I assume I could obtain a 44% DMSO solution by adding 78,57 mL of DMSO to the 100mL of 10% PVI (78,57/(100+78,57)).
On the other hand the PVP-I concentration in this new solution would drop to 5,6% (10mg/178,57).
Is that correct?
Is there a way I can obtain both 44% DMSO and 1% PVP-I ?
Thanks,
Giuseppe
I am trying to make a solution described in a published study but I am not sure on how to interpret it correctly:
"We have been using a low-dose formulation of 1% Povidone-Iodine (w/w) in a solution containing dimethyl sulfoxide (DMSO)...
"1% povidone–iodine solution in a liquid vehicle system that included 44% USP-grade DMSO"Now I can easily find pure liquid DMSO but only a 100mL of 10% w/v Povidone-Iodine (PVP-I).
Based on my (limited..) understanding, I assume I could obtain a 44% DMSO solution by adding 78,57 mL of DMSO to the 100mL of 10% PVI (78,57/(100+78,57)).
On the other hand the PVP-I concentration in this new solution would drop to 5,6% (10mg/178,57).
Is that correct?
Is there a way I can obtain both 44% DMSO and 1% PVP-I ?
Thanks,
Giuseppe