Help with syringe pressure and Students T test

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SUMMARY

The discussion focuses on the relationship between syringe size and negative pressure generated during aspiration, specifically comparing 5 ml and 10 ml syringes. The experiment utilized a Digitron electronic manometer to measure negative pressure, yielding average readings of 56.4 cm Hg for the 5 ml syringe and 31.5 cm Hg for the 10 ml syringe. The user seeks to validate the hypothesis that smaller syringes produce higher negative pressure using a Student's t-test, and inquires about performing this analysis using Microsoft Excel.

PREREQUISITES
  • Understanding of negative pressure measurement techniques
  • Familiarity with the Student's t-test statistical method
  • Basic knowledge of Microsoft Excel for data analysis
  • Concept of aspiration force in relation to syringe volume
NEXT STEPS
  • Learn how to perform a Student's t-test in Microsoft Excel
  • Research the principles of negative pressure and its clinical implications
  • Explore the effects of syringe size on aspiration force and pressure
  • Study statistical significance and interpretation of t-test results
USEFUL FOR

Medical professionals, researchers in clinical settings, and anyone interested in the physics of syringes and aspiration techniques will benefit from this discussion.

madpsychic
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I am a doctor with limited mathematics knowledge. I am trying to prove to my medical fraternity that for a given force of aspiration, a smaller syringe generates a higher "negative pressure". I did a small experiment. I hung an one kilogram weight on a 5 ml and 10 ml syringe and connected it to a Digitron electronic manometer. I got the following neg pressure readings (cm Hg).
The 5 ml syringe: 57.3;55.8;56.7;56.6;55.9;56.6;57.4;56.1;56.1;56.6 The 10 ml syringe gave the following: 32.8;32.3;30.7;31.9;31.9;32.6;30.6;33.3;32.1;30.5
I would like to"scientifically" say that the smaller syringe creates a bigger negative pressure.
Would a "Students t" test be an appropriate one to use ? Can I use MS excel do do the test ?

With regards to the posting by light_bulb: for each reading , i gave a 30 second time period for the readings to settle. Hopefully that will look after the time aspect of things ?
 
Last edited:
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you'll be using more force in the same amount of time to compensate for filling more volume, so unless your juggling the amount of force or time the larger syringe will create a higher negative pressure.

i'd just put it down like ml / seconds * 0.19336779 = psi a second at 0 degrees c
 
Last edited:

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