How Precise Can Insulin Pump Pistons Deliver Micro Doses?

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Discussion Overview

The discussion revolves around the precision of insulin pump pistons in delivering micro doses of insulin, specifically focusing on the mechanics of piston movement and the measurement of insulin units. The scope includes technical explanations and considerations related to the design and functionality of insulin delivery systems.

Discussion Character

  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant questions the difficulty of achieving precise movement of a piston to deliver micro doses of insulin, specifically asking about the feasibility of moving the piston to deliver 0.05 of a unit.
  • Another participant suggests that using a stepper motor with a screw drive setup could facilitate precise movement of the piston.
  • A similar suggestion is made regarding the use of a microstepper motor with the screw drive for enhanced precision.
  • A participant provides clarification on the measurement of insulin units, noting that there is no SI prefix for 1x10^-5 and converting the volume of insulin units into milliliters, stating that each unit corresponds to 1 mL in a 200 mL cartridge.
  • The same participant mentions that 0.05 mL is approximately the volume of one drop of water and discusses the regulation of intravenous drips by counting drops, highlighting variability in drop volumes across different drippers.

Areas of Agreement / Disagreement

Participants express differing views on the complexity of achieving precise piston movement, with some asserting it is manageable with specific motor setups while others focus on the measurement and implications of insulin dosing. The discussion remains unresolved regarding the best approach to achieve the desired precision.

Contextual Notes

There are limitations in the discussion regarding the assumptions made about the mechanics of piston movement and the definitions of measurement units. The relationship between drop volume and insulin dosing is also not fully explored.

Nerdydude101
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So in an insulin pump there is a cartridge that holds 200 mL of insulin, this is broken into 200 "units" of insulin (i would use metric but i can't seem to find the proper metric prefix for 1x10^-5). The piston is controlled by a microprocessor and gives these very small "units" of insulin, the smallest it can give is .05 of one of the "units" my question is how hard is it to get a piston to move that exactly?
 
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not that hard if you use a stepper motor with a screw drive setup.
 
thankz said:
not that hard if you use a stepper motor with a screw drive setup.

Or even a microstepper motor with the screw drive... :biggrin:
 
There is no SI prefix for 1x10^–5. It is 10x10^–6 = 10 u.
If a 200 mL cartridge holds 200 “units” then each unit is 1 mL.

0.05 mL is an interesting volume. It is the approximate volume of one drop of water.
If you use a common eye dropper, 20 drops = 1 mL.

Intravenous drips are regulated by counting drops.
Different profile drippers have different drop volumes. Standards are 10, 15, 20 or 60 drops per mL.

http://en.wikipedia.org/wiki/Drop_(unit)
 

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