Immunotherapy Cures Woman of Breast Cancer

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The discussion centers on a successful immunotherapy case where a woman was cured of breast cancer by utilizing her own T-cells. Lymphocytes from her tumor were extracted, multiplied, and reinjected, leading to her being cancer-free for two years. The Science News article highlights that T-cells can be specifically primed to target different diseases, recognizing unique foreign proteins. This specificity allows immune cells to distinguish between healthy cells and mutated cancer cells, which is crucial for effective immunotherapy.

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lymphocytes from her tumor were taken out.
Those reacting to her tumor were multiplied an injected back into her.
She has been cancer free for two years.
Science News article here.
 
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Biology news on Phys.org
Interesting. It says they removed T-cells from her body and then used the ones primed to attack the tumor cells. Are different T-cells primed to attack different types of diseases?
 
Each immune cell recognizes a specific part of a specific foreign protein. So, an immune cell that recognizes a protein from a specific virus is primed to attack that virus (and only that virus). Immune cells normally will not recognize "self" proteins made by the body. This prevents immune cells from attacking healthy cells (though sometimes this goes wrong in autoimmune diseases). Cancer, however, is caused by mutations to various proteins, and sometimes these mutant proteins can be recognized as non-self by immune cells. Immune cells that recognize these mutated cancer genes can help fight cancer and are the ones that are useful for immunotherapy.
 
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