The discussion centers on the best polymerization method for manufacturing high molecular weight polymer drug hosts. Participants express uncertainty about the availability of expert advice on this specific and potentially proprietary topic. There is a suggestion for the original poster to provide more details and demonstrate prior research to elicit better responses. The conversation hints at the possibility that the inquiry may resemble homework, which raises concerns about the forum's guidelines on homework help. Overall, the topic remains complex and may not receive the necessary expertise within the forum.