Insulin Resistance and Cell Signaling

AI Thread Summary
Insulin resistance can occur due to insufficient insulin production by the pancreas or dysfunction of insulin receptors. Additional factors contributing to insulin resistance may include inflammation, obesity, and genetic predispositions. The discussion also touches on the variability in cellular responses to insulin signaling, highlighting that different cell types exhibit distinct signaling pathways and reactions. The participants are evaluating various investigations to determine which provides the most compelling evidence for insulin resistance and cellular signaling, with a preference expressed for one particular study. The importance of proper citation for sources and images used in the discussion is emphasized, underscoring the need for academic integrity.
infinite.curve
Messages
23
Reaction score
1
Well, I am confused on insulin resistance and cellular signaling.

Know... Below is my understand:

Insulin resistance happens either when the paceraes does not produce enough of the protein insulin and another way resistance occurs is when the receptor is not functioning properly. Are there other ways of insulin resistance?

Also, how are different type of cells types differ in the amount of reactions? Like, what is the signaling in cell signaling that makes for a certain amount of stop if reaction?

I have attached a picture to show the signaling in steps. Also, another picture just to see which do you guys think is the better investigation of the 4 that shows the best evidence for insulin resistance and cell signaling.

I personally thought that the first investigation was best representing of insulin resistance and cell signaling, but what is your opinion? Which one has more evidence?

http://file///C:/Users/HP8440p-PC/Desktop/FullSizeRender.jpg
http://file:///C:/Users/HP8440p-PC/Desktop/FullSizeRender%20(1).jpg
FullSizeRender (1).jpg
FullSizeRender.jpg
FullSizeRender (1).jpg
FullSizeRender (1).jpg
FullSizeRender (1).jpg
FullSizeRender (1).jpg
 

Attachments

  • FullSizeRender (1).jpg
    FullSizeRender (1).jpg
    53.5 KB · Views: 681
  • FullSizeRender.jpg
    FullSizeRender.jpg
    18.5 KB · Views: 681
Last edited by a moderator:
Biology news on Phys.org
infinite.curve said:
I have attached a picture to show the signaling in steps. Also, another picture just to see which do you guys think is the better investigation of the 4 that shows the best evidence for insulin resistance and cell signaling.
Please post a link to the source of the images posted.
 
Thank you, we always need to credit the author.
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom
Back
Top