Ion acccount in neuron after firing

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Discussion Overview

The discussion revolves around the mechanisms of ion concentration changes in neurons after firing, specifically focusing on sodium and potassium ions. Participants explore how these ion concentrations return to their original states following an action potential, touching on the roles of various ion channels and pumps involved in this process.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification

Main Points Raised

  • One participant inquires about the process by which sodium ions become rich and potassium ions become poor in a neuron after firing, and how these concentrations return to their original states.
  • Another participant references animations and experiments that suggest it takes many action potentials to significantly alter ion concentrations, indicating that the sodium-potassium pump plays a crucial role in this process.
  • There is a discussion about the existence of three types of channels: potassium, sodium, and a potassium-sodium channel, with one participant seeking clarification on their roles in firing and resetting ion concentrations.
  • A later reply confirms the general understanding of the roles of these channels while noting that there are many other channels that can vary among different neurons.

Areas of Agreement / Disagreement

Participants generally agree on the basic roles of sodium and potassium channels in neuron firing and resetting ion concentrations, but the discussion includes varying levels of detail and understanding regarding the specific mechanisms and additional channels involved.

Contextual Notes

The discussion does not resolve the complexities of ion channel interactions or the specific mechanisms by which ion concentrations are restored, leaving some assumptions and details unaddressed.

sweet springs
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Hi.

I am learning how neuron transmit current. I am wondering after firing sodium ions are rich and potassium ions are poor in neuron cell. How ion concentrations come back to the original states before firing?

Thanks for your help in advance.
 
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http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__how_the_sodium_potassium_pump_works.html
http://hyperphysics.phy-astr.gsu.edu/hbase/biology/nakpump.html

It takes many action potentials to deplete ion concentrations to the extent the action potentials change their shape. This can be estimated from experimets in which the sodium-potassium pump is poisonsed, and the cell made to fire action potentials.
 
Last edited:
Thanks atvy.
Your animations together with http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter14/animation__the_nerve_impulse.html
mean that there are three channels so to say potassium, sodium and potassium-sodium. The first two are players of firing and the last one reset the neuron ion concentration. Do I understand right?
Regards.
 
sweet springs said:
Thanks atvy.
Your animations together with http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter14/animation__the_nerve_impulse.html
mean that there are three channels so to say potassium, sodium and potassium-sodium. The first two are players of firing and the last one reset the neuron ion concentration. Do I understand right?
Regards.

Yes. There are many other channels that vary from neuron to neuron, but you have the general picture right.
 
atvy, thanks a lot.
 

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