Is it possible to kill a virus for good

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SUMMARY

This discussion centers on the possibility of permanently killing viruses, specifically referencing the influenza virus and the eradication of smallpox. It is established that viruses rely on proteins for infection and replication, and methods such as UV radiation, bleach treatment, and dehydration can irreversibly damage these proteins, rendering the virus non-infectious. The 1918 flu outbreak and the subsequent rediscovery of the virus in 1950 illustrate that while viruses can become inactive, they can also be permanently destroyed through specific treatments.

PREREQUISITES
  • Understanding of viral structure and replication mechanisms
  • Knowledge of disinfection methods, including UV radiation and chemical treatments
  • Familiarity with the concept of viral inactivation and eradication
  • Basic awareness of historical viral outbreaks, such as smallpox
NEXT STEPS
  • Research the mechanisms of viral inactivation through UV radiation
  • Explore the use of bleach in disinfecting surfaces contaminated with viruses
  • Study the "ring vaccination" technique used in smallpox eradication
  • Investigate the structural components of viruses that are targets for destruction
USEFUL FOR

Virologists, public health officials, and anyone involved in infection control and disease prevention will benefit from this discussion.

hivesaeed4
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Hi,

Previously, I thought like everyone else that viruses were alive inside and dead outside the hosts body. However recently I read a book which discussed diseases. According to it, (the scan of the page is attached) there was an outbreak of a virus caused disease (flu) in 1918 in Alaska. In 1950, the virus was rediscovered and it did'nt infect suitable hosts because it was dead. Does this mean that it is possible to kill a virus for once and for all. If so, what methods are used for killing the virus and as a result of such methods what goes wrong in the virus which makes it rest in peace.

Regards.
 

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Biology news on Phys.org
Viruses are rely on many proteins to be able to infect host cells, replicate its genetic material, and create new viruses. For example, influenza (the causative agent of flu) has proteins in its outer envelope that allow it to attach to cells, enter into the cell, and release its RNA for replication. Any treatments that damage these proteins (for example, by causing them to unfold) or the genetic material of the virus, will cause the viruses to be noninfectious. For example, irradiating a surface with UV radiation or treating it with bleach will irreversibly damage the viral particles and render them non-infectious. Simply leaving the virus to dry out on a surface will eventually inactivate the virus as well (because the component proteins will irreversibly unfold in the absence of water as it dehydrates).
 
An example of an eradicated virus is smallpox, there a "ring vaccination" technique was used to isolate cases and vaccinate the people in the vicinity.

http://www.who.int/mediacentre/factsheets/smallpox/en/
 
hivesaeed4 said:
Previously, I thought like everyone else that viruses were alive inside and dead outside the hosts body.

The concept of dead and alive becomes really hazy with things like viruses. By alive inside they actually mean the viruses can replicate only in a host while dead outside doesn't really mean that they are gone for good but just sort of an inactive state. That said, viruses can be permanently destroyed by damaging any vital structural component of the theirs.
 

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