Is the Immune Response to Nickel Metal Responsible for Nickel Allergies?

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SUMMARY

Nickel allergy is primarily caused by nickel salts, not the nickel metal itself. This allergy manifests as contact dermatitis, triggered when nickel interacts with perspiration, leading to corrosion of jewelry or watches. The immune response to these nickel salts is what results in allergic reactions. Understanding this mechanism is crucial for managing and preventing nickel allergies.

PREREQUISITES
  • Basic understanding of allergic reactions and immune responses
  • Knowledge of corrosion processes in metals
  • Familiarity with contact dermatitis and its symptoms
  • Awareness of nickel and its compounds in everyday items
NEXT STEPS
  • Research the chemical properties of nickel salts and their role in allergies
  • Explore methods to prevent corrosion in jewelry to reduce nickel exposure
  • Learn about alternative materials for hypoallergenic jewelry
  • Investigate treatments for contact dermatitis caused by nickel allergies
USEFUL FOR

Individuals with nickel allergies, dermatologists, jewelers, and anyone involved in the design or manufacturing of jewelry and accessories.

praeclarum
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Nickel allergy is a very common allergy. It causes contact dermatitis. But why is it allergenic, being a metal. Recall that allergies are caused by an immune response. What exactly are you reacting to -- the nickel metal itself??
 
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Well a quick Google turns up this:
http://corrosion-doctors.org/Allergies/images/Pierced.jpg

Sorry, I meant this:

In fact the allergy is not caused by nickel itself but by the nickel salts which are formed under the effect of perspiration in contact with the piece of jewellery piece or watch. This phenomenon is always accompanied by corrosion of the object.
http://corrosion-doctors.org/Allergies/nickelallergy.htm
 
Interesting! Thank you.
 

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