There are two answers to this, depending on what you mean:
From context it sounds like you're talking about a jet of air, in which case you should read about
rocket engine nozzles, because the shape of the nozzle most definitely does impact the force output.
The other is the idea that you could use this air to pressurize a bladder of some sort, to lift a large load. (Think something like an air mattress.) In this situation, the force you could apply would be equal to the surface area times the pressure. Thus, 60 inches * 80 inches * 150 pounds per square inch gives you 720,000 pounds.
There's a really big difference between these scenarios. That's why were asking you what you're trying to accomplish. We don't fully understand your question.