Meiosis in cell with odd diploid number

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Discussion Overview

The discussion revolves around the implications of meiosis in a cell with an odd diploid number, specifically 2n=15. Participants explore the potential outcomes of meiosis in such a scenario, touching on concepts of chromosome pairing, aneuploidy, and associated genetic disorders.

Discussion Character

  • Exploratory
  • Debate/contested
  • Conceptual clarification

Main Points Raised

  • One participant proposes that in a cell with 15 chromosomes, there would be 7 pairs of homologous chromosomes and 1 unpaired chromosome, leading to 7 chromosomes in one daughter cell and 8 in another after Meiosis I.
  • Another participant mentions that an odd number of chromosomes often results from nondisjunction, leading to aneuploidy, which is associated with various genetic disorders.
  • A third participant clarifies that the initial example is not truly diploid and emphasizes that aneuploid organisms typically face significant fertility issues and cannot produce viable gametes.
  • A later reply introduces Turner's Syndrome as an example of aneuploidy involving the X chromosome, suggesting a connection to human genetics.

Areas of Agreement / Disagreement

Participants express differing views on the implications of meiosis in cells with odd diploid numbers, with some agreeing on the challenges posed by aneuploidy while others focus on the specific mechanics of chromosome distribution during meiosis.

Contextual Notes

The discussion includes assumptions about chromosome behavior during meiosis and the implications of aneuploidy, but these aspects remain unresolved and are subject to further exploration.

stfz
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I've come across a question which is asking what would happen in a cell with odd diploid number 2n=15 when it undergoes meiosis. Here's my thinking:
- 15 chromosomes, so 7*2 homologues + 1 loner?
- Hence, after Meiosis I, we'd have 7 chromosomes in one cell, and 8 in the other?
- After meiosis II, we'd have 2 cells with 7 chromosomes, and 2 cells with 8?

Just wanted to check that this is a plausible answer for this situation? It seems a bit rare, and odd 2n appears to be associated with infertility (e.g. mules).

Would appreciate a confirmation of this :) Thanks!
 
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An odd number of chromosomes is often the result nondisjunction...the chromosomes don't separate properly. The term aneuploidy is used for such an abnormal number of chromosomes. Many genetic disorders are associated with odd numbers of chromosomes. Down's syndrome in humans for example...but there are also examples of people who have extra sex chromosomes who live normal lives...XXY trisomy for example.
 
@Megaquark is correct - that example is NOT diploid. And since you see why meiosis has problems, aneuploid organisms, if they live long enough to attempt reproduction, have serious issues with fertility. They cannot create viable gametes generally.
 

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