Mendelian's - epitasis 9:3:4 , biology

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Discussion Overview

The discussion revolves around the genetic ratios observed in a dihybrid cross involving corn, specifically focusing on the 9:3:4 phenotypic ratio. Participants explore the implications of this ratio in terms of epistasis and gene interactions, seeking to understand the inheritance patterns and biochemical influences at play.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • One participant presents data from a corn count resulting in 267 yellow, 97 white, and 144 purple kernels, questioning the implications of a 9:3:4 ratio and its relation to recessive epistasis.
  • Another participant challenges the initial claim by stating that the data alone does not constitute a phenomenon without context, asking for details about the genetic cross or ancestry involved.
  • A third participant describes the dihybrid cross between purple (rrCC) and white (RRcc) parents, explaining that the F1 generation is all yellow (RrCc) and leads to the observed F2 generation ratio of 9:3:4.
  • One participant proposes a potential explanation for the observed ratios, suggesting that the 9:3:4 ratio can be derived from the expected frequencies of genotypes in a dihybrid cross, while noting that there may be multiple interpretations of the data.
  • Another participant expresses frustration at unanswered questions and emphasizes the importance of familiarity with genetic concepts, suggesting that the observed ratios can be explained by the independence of the R locus and the C locus, leading to specific expected frequencies.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the interpretation of the data or the underlying genetic mechanisms. Multiple competing views and interpretations of the observed ratios remain present throughout the discussion.

Contextual Notes

Participants note the need for additional context regarding the genetic cross and the ancestry of the corn to fully understand the implications of the observed ratios. There are unresolved aspects regarding the specific gene interactions and the assumptions made in the interpretations.

cliffordlim
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After I have done counting the corn and the result 267 yellow , 97 white , 144 purple
ratio 9:3:4 respectively . Recessive - Epitasis ?
I have no idea create a inheritance cross and the biochemical influence by genes interaction from
this phenomena
 
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cliffordlim said:
After I have done counting the corn and the result 267 yellow , 97 white , 144 purple
ratio 9:3:4 respectively . Recessive - Epitasis ?
I have no idea create a inheritance cross and the biochemical influence by genes interaction from
this phenomena

That by itself is not a phenomenon. If I told you the number of books of different colours on my shelves would that be a phenomenon?

You have to state what this corn your counted has come out of. Some cross? The total descendance after n=? generations from two ancestors? Something else?
 
This is the dihybrid cross where the parents are purple ( rrCC ) x white ( RRcc)
F1 generation all RrCc(yellow ).The result is F2 generation in the ratio 9:3:4 . (Yellow:white:purple)
What kind of gene interaction is this and how should I explain it?
 
I can't say I ever met this sort of situation before, but I found a, repeat a, possible solution so it Is not a question of expertise, just thinking.

9 + 3 + 4 = 16, convenient. Take one gene and the three genotypes are in ratio 1/4: 2/4: 1/4 or 4/16: 8/16: 4/16 . You can probably see where your 4/16 purples are coming from. I wrote out a tree - top layer

RR. Rr. rr
4. 8. 4Then on next layer wrote the three genotypes that come under each of those in F2 with their expected frequencies in sixteenths.

Excluding the purples I looked for what combinations of c/C's do I see 3 of? There seems to be more than one answer, I don't know if there is other information to distinguish these, but getting that far is the main thing.
 
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OP not come back, not recommending self for any future help but I think it is a shame to leave questions unanswered like this when the answer is so simple yet maybe not at first sight obvious.

Point is a bit of familiarity helps a lot with genetics - geneticists can look at quite complicated data and reel you off the explanation just like that while you have to work it out more slowly on paper, in fact I wrote myself out the genotype frequencies as mentioned in #4.

But then I see, just in your head, what can explain 3/16 whites? Simples - first the data indicated that RR makes purple independent of the C locus, but presence of two R necessary for it. That is 4/16 cases, now of the 12 left 3 are white, that's just the expected 1/4 of homozygous for C, when you have 1:2:1 i.e. 3:6:3 of cc:Cc:CC. White recessive.
 

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