Recently, I have read a lot about the physics behind negative refraction, super lenses, meta-materials and the like and I think I understood the theory to quite some detail. Negative refraction was predicted first by sowiet physicists around Mandelshtam [1,2], and, a paper by Veselago [3,4], who predicted a plain sheet of these materials to act like a lens. This work was quite forgotten until Pendry  showed in the new century that these "Veselago lenses" may even act as perfect lenses which circumvent resolution criteria. Pendry also constructed some devices which act like a negative index material for microwaves. Since then numerous papers have appeared and there seems to be some war between physicists who treat this with methods from traditional optics, and electrotechnitians, who try to construct smaller and smaller microstructures to achieve the effect. Although work from the 1960ies looked for this effect in ordinary crystals, like sodium uranyl acetate, in recent articles, it is taken for granted that negative refraction is an effect which requires "meta-materials", which have to be constructed with methods as used in the production of microchips and are very expensive. As a chemist I wonder why no chemists take up the gauntlet? After all, there seem to be many methods to potentially synthesize such substances, like supramolecular chemistry. Another possible route would be via crystals of high optical activity but being optical isotropic, like the uranyl compound mentioned at the beginning. Or does anybody know of chemistry groups working on that field? 1. Agranovich, Vladimir M., and Yu N. Gartstein. "Spatial dispersion and negative refraction of light." Physics-Uspekhi 49.10 (2006): 1029. 2. Agranovich, Vladimir M., and Vitaly Ginzburg. Crystal optics with spatial dispersion, and excitons. Springer, 1984. 3. Veselago, Victor Georgievich. "THE ELECTRODYNAMICS OF SUBSTANCES WITH SIMULTANEOUSLY NEGATIVE VALUES OF IMG align= ABSMIDDLE alt= ϵ eps/IMG AND μ." Physics-Uspekhi 10.4 (1968): 509-514. 4. Veselago, Victor, et al. "Negative refractive index materials." Journal of Computational and Theoretical Nanoscience 3.2 (2006): 189-218. 5. Pendry, John Brian. "Negative refraction makes a perfect lens." Physical review letters 85.18 (2000): 3966.