Nernst potential and reverse potentials

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SUMMARY

The discussion focuses on calculating the Nernst potential and reversal potentials for ions, specifically sodium (Na+), potassium (K+), and chloride (Cl-), given their concentrations inside and outside the cell. The participants seek clarity on using Fick's law for these calculations. The reversal potential for a conductance equally permeable to sodium and potassium can be determined using the Goldman equation, while the Nernst potential for each ion can be calculated using the Nernst equation based on the provided concentration values.

PREREQUISITES
  • Understanding of Nernst equation and its application
  • Familiarity with Goldman equation for reversal potential
  • Knowledge of ion concentration gradients
  • Basic principles of electrochemistry
NEXT STEPS
  • Study the Nernst equation and its derivation for ion concentration calculations
  • Learn how to apply the Goldman equation for mixed ion conductance scenarios
  • Explore Fick's law and its relevance to ion diffusion
  • Review case studies on membrane potentials in cellular biology
USEFUL FOR

Students and professionals in cellular biology, biophysics, and neurobiology, particularly those interested in membrane potentials and ion transport mechanisms.

madbeemer
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I know the following
ion/inside cell/outside cell
Cl- 5mM 150 mM
K+ 130mM 5mM
Na+ 20mM 140mM
Ca2+ 10^-4mM 2mM

How would I find the reversal potential for conductance equally permeable to sodium and potassium?
How do I find the reversal potential for a conductance equally permeable to sodium, potassium, and chlorine?
Also, how do I find the nernst potential for each ion at the below external and internal concentrations?
 
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Helllp, please! I tried and phailed T_T

You use fick's law to get nernst right?
 
madbeemer said:
Helllp, please! I tried and phailed T_T

You use fick's law to get nernst right?
Have you looked at this?
 
Yes. How I use it?
 
For reversal potential
 

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