Nernst potential and reverse potentials

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Discussion Overview

The discussion revolves around calculating the reversal potential and Nernst potential for various ions based on their concentrations inside and outside of a cell. Participants are exploring the methodology for determining these potentials, particularly in scenarios where conductance is equally permeable to sodium and potassium, as well as to sodium, potassium, and chlorine.

Discussion Character

  • Homework-related
  • Mathematical reasoning

Main Points Raised

  • One participant provides the concentration values for chloride, potassium, sodium, and calcium ions inside and outside the cell.
  • Another participant expresses difficulty in calculating the Nernst potential and suggests using Fick's law for the calculations.
  • A later reply seeks clarification on how to apply Fick's law to find the Nernst potential.
  • There is a mention of the reversal potential in relation to the conductance of ions.

Areas of Agreement / Disagreement

The discussion remains unresolved, with participants expressing uncertainty about the methods to calculate the potentials and seeking further clarification.

Contextual Notes

Participants have not reached consensus on the appropriate methods or formulas for calculating the Nernst and reversal potentials, and there are indications of missing steps or assumptions in their reasoning.

madbeemer
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I know the following
ion/inside cell/outside cell
Cl- 5mM 150 mM
K+ 130mM 5mM
Na+ 20mM 140mM
Ca2+ 10^-4mM 2mM

How would I find the reversal potential for conductance equally permeable to sodium and potassium?
How do I find the reversal potential for a conductance equally permeable to sodium, potassium, and chlorine?
Also, how do I find the nernst potential for each ion at the below external and internal concentrations?
 
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Helllp, please! I tried and phailed T_T

You use fick's law to get nernst right?
 
madbeemer said:
Helllp, please! I tried and phailed T_T

You use fick's law to get nernst right?
Have you looked at this?
 
Yes. How I use it?
 
For reversal potential
 

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