Neurophysics vs computational neuroscience

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Discussion Overview

The discussion explores the differences between neurophysics and computational neuroscience, particularly focusing on the engineering perspective related to brain signal analysis and signal processing. It examines whether these approaches are primarily practical or if they contribute to scientific understanding and discovery regarding brain function.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • One participant questions the distinction between neurophysics and computational neuroscience, suggesting it may be largely semantic.
  • Another participant highlights that computational neuroscience often simplifies neuron behavior to spiking mechanisms, while bioengineering may involve more complex interactions using Maxwell's equations.
  • Examples of applications in bioengineering, such as cochlear implants and deep brain stimulation, are provided to illustrate practical uses of engineering in neuroscience.
  • Concerns are raised about whether engineering approaches are limited to practical applications like noise reduction or if they can lead to new scientific discoveries about brain function.
  • There is an interest in understanding which approach—neurophysics or computational neuroscience—might be more promising for understanding the brain.

Areas of Agreement / Disagreement

Participants express differing views on the significance of the distinctions between neurophysics and computational neuroscience, with some suggesting that the differences may not be substantial. The discussion remains unresolved regarding the implications of these approaches for scientific discovery versus practical application.

Contextual Notes

Some assumptions about the definitions of neurophysics and computational neuroscience are not fully explored, and the discussion does not clarify the extent to which engineering methods contribute to theoretical understanding.

Neuroni
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What's the difference between above-mentioned fields?

Moreover how engineering perspective focused on brain signal analysis and signal processing differ
from those?
Is this approach only for practical purposes like noise reduction from signals and detecting signals which we already understand for example diagnostic applications. And when you have made your filter ready and find something new which isn't yet discovered the one who get to investigate the results is someone else. Or are there science in this approach also in a sense that you can study and explain how the the brain works and make new discoveries with these signals and systems methods.

I'm very interested in the engineering perspective because it gives you a possibility for biomedical engineering which is one of my interest also. I'm just worried about the things i wrote above.

Which one of these approaches do you think is best(promising) for understanding the brain and why?

If someone could help me with this i would really appreciate it.

Thanks for your help.
 
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I suspect the difference is largely semantics - differences in wording that for all practical purposes mean the same thing.

I'm not sure I understand the second part of your question. There is a lot of signal processing involved in biomedical engineering.
 
Where did you see the term "neurophysics"?

One difference in tendency between computational neuroscience and bioengineering is the extent to which one uses Maxwell equations. In computational neuroscience, one is often interested in how networks of neurons behave, and the neurons are treated very simply as things that spike once they get input above a certain threshold, analogous to a logic gate. In contrast, in bioengineering one may want to stimulate the neurons to achieve a certain effect, in which case one may use Maxwell's equations to consider how various electrode configurations stimulate the neurons.

As an example, computational neuroscience might use tools like http://www.briansimulator.org/ or http://www.nest-initiative.org/index.php/Software:About_NEST .

Bioengineering would be things like the cochlear implant, the auditory brainstem implant, the trial http://www.bioen.utah.edu/cni/projects/blindness.htm, deep brain stimulation for Parkinson's, and brain-machine interfaces.

The distinction is of course not hard and fast.

Also there are many other people involved in making these things work - drug addicts, for example, made a huge contribution in the eventual development of deep brain stimulation. http://www.parkinsonsappeal.com/dbs/dbshistory.html
 
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