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What to know about the Nipah virus
https://www.cnn.com/2026/01/29/health/nipah-virus-explainerThe World Health Organization reported two cases of a rare virus in an eastern Indian state on Thursday.
The virus — called Nipah — kills more than half of the people it infects. Nipah virus, which was named after the village in Malaysia where the first known patient lived, is part of the same family of viruses as measles. Despite that, it’s not as infectious as measles, but it is significantly more deadly.
How is it transmitted?
Nipah is a zoonotic virus, meaning it can be transmitted from animals to humans. Most commonly, that happens through direct contact with an infected pig or bat, according to the US Centers for Disease Control and Prevention. Eating fruits or fruit products — such as raw date palm juice — contaminated with urine or saliva from infected fruit bats also contributes to spread.
I heard about the new infections this morning. Apparently, there is no vaccine, and the virus has between a 40% to 75% mortality rate.
We have several threads that discuss the Nipah virus and cases.
Nipah virus fears trigger airport checks across Asia after India confirms two cases
https://www.reuters.com/business/he...s-thai-malaysia-step-up-screening-2026-01-28/Everything to know about Nipah virus amid cases being detected in India
https://abcnews.go.com/Health/nipah-virus-amid-cases-detected-india/story?id=129667635WHO - Nipah virus
https://www.who.int/news-room/fact-sheets/detail/nipah-virus
Ref: https://en.wikipedia.org/wiki/Nipah_virusLike other henipaviruses, the Nipah virus genome is a single (non-segmented) negative-sense, single-stranded RNA of over 18 kb, which is substantially longer than that of other paramyxoviruses.
Is an mRNA vaccine possible?
From 2018 Nature - mRNA vaccines — a new era in vaccinology - https://www.nature.com/articles/nrd.2017.243
mRNA-lipid nanoparticle vaccines provide protection against lethal Nipah virus infection
https://www.nature.com/articles/s41541-025-01336-1
Designing next-generation mRNA vaccines against nipah virus using predictive immunoinformatics frameworks
https://www.sciencedirect.com/science/article/pii/S3050787125000356