Ok, if I understand what
@pervect is getting at, it is that you can set up spatial coordinates in a physically realized inertial frame without using clocks (e.g. set up a network of bodies at mutual rest as define by no Doppler, and measure positions using a physical measuring body). Then proper velocity (a standard term, though not well chosen) can be measured for any test body (not light) with one clock on the body, distance determined by labels on the realized frame.
I claim that any such standard construction assumes isotropy (e.g., no Doppler = mutual rest, in all directions, implicitly assumes isotropy; so does the notion of Newtons laws holding in their simplest form).
But once you let isotropy slip in, there is simply no distinction between one way and two way speed, for light, or anything else. So, under assumption of isotropy, just measure two way speed of light with one clock and state it is also one way by assumption of isotropy.