Phys-Org Medical Xpress prostate cancer 'Golden Era

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The discussion centers on the article "Golden age of prostate cancer treatment hailed as fourth drug in two years extends life," which reports a survival extension of 1 to 1.5 years for metastatic prostate cancer patients. Critics argue that a mere six months of added survival does not constitute a 'Golden Age' in treatment. The need for responsible evaluation of PR news releases and the importance of peer-reviewed sources is emphasized. The US FDA's "Priority Review designation" for the drug is noted, along with the credibility of institutions like MSKCC involved in the trials.

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Phys-Org Medical Xpress prostate cancer 'Golden Era"

The article "Golden age of prostate cancer treatment hailed as fourth drug in two years extends life" has attracted my attention, just a few weeks following my surgery for prostate cancer. Because the study tracks cancer that has metastasized from prostate cancer to more lethal forms of remotely located prostate cancer, I am interested in the study.

This "Golden Age" that has been "hailed" is the report of lengthening the survival of patients from 1 to 1.5 years. Six months of added life (more accurately quoted as 'survival', not as any quality of life) is 'hailed'?. This is a Golden Age?

Six months added life is Physorg's definition of a 'Golden Age'?

Of course, it is not.

There needs to be some mechanism in place that responsibly evaluates PR news releases, instead of simple parroting their content, at the breathless level of PR agents, as opposed to direct interviews of the scientists responsible for the submission to the peer-reviewed scientific literature.

Since PhysOrg makes itself available to unsophisticated readers, it has an essential responsibility to evaluate the source(s) of information reported, and an honest (peer-reviewed) evaluation of the contents that PhysOrg reports.

When self-interest reports are implicitly rubber-stamped as 'facts', we are all poorer for experience.
 
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Additional info at Medscape http://www.medscape.com/viewarticle/769167 I deal largely in radiation therapy, but a few things to note. Local, regional, and distant control, as well as pain relief are significant objectives for any patients. While this isn't a cure, slowing the process and improving the quality of life are still very positive advances. The US FDA has given a "Priority Review designation" to this drug, and the Phase III trials are not indicators of a rubber stamp. Additionally, being able to demonstrate the effectiveness sufficiently to be able to stop the trial and get the Priority Review designation for the drug isn't done lightly. MSKCC and the other institutions involved in the trials are very creditable.
 

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