Possible to find amount of a substance in tissue sample?

[GREENEMAC]

If one has a tissue sample that contains a known substance (specifically a polymer hydrogel of poly[N-(2-hydroxypropyl) methacrylamide), is there a way to quantify the amount of that substance in the sample, or a way to compare the relative amount of the substance in multiple tissue samples?

 

[Borek]

Whole analytical chemistry deals with methods designed to solve this type of the question. I suppose the answer is yes - but for details you will need to consult literature.