Powerpoint 2013 Issue Opening Presentation

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The issue of being unable to open a PowerPoint presentation often stems from antivirus software blocking access due to potential threats. Users are advised to ensure their antivirus is up-to-date and functioning properly. If the problem persists, disabling the antivirus temporarily may help, but caution is advised as this could expose the system to malware if the file is indeed infected. Additionally, the error message can also indicate problems related to file permissions, especially if the file was restored, copied, or downloaded in a way that retains original source permissions. Users should check the file's properties and security settings against a functioning file to identify any discrepancies that may be causing the issue.
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When I open a powerpoint presentation that I created I get the following message:The presentation cannot be opened. Your antivirus program may prevent you from opening the presentation. To fix this problem, make sure your antivirus program is current and working correctly. If the problem persists and the presentation is from someone that you trust, turn off your antivirus program, and then try to open the presentation again. If you do this, make sure you turn on your antivirus program again after you open the presentation.

I have disabled the AV and the error message still occurs. I have tried both Powerpoint 2003 and Powerpoint 2007.
 
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The message was probably just a ploy to get past your antivirus. Antivirus software is designed to keep you from opening infected software. The only thing that was probably in the presentation was a virus. By turning off your AV and clicking on the presentation, you have very likely infected your computer.
 
Borg said:
The message was probably just a ploy to get past your antivirus. Antivirus software is designed to keep you from opening infected software. The only thing that was probably in the presentation was a virus. By turning off your AV and clicking on the presentation, you have very likely infected your computer.

This is a definite possibility and the OP shouldn't discount running a thorough AV scan, but the message is also a real Microsoft message that can trigger from various scenarios related to file permissions - for example restoring / copying / downloading a file in such a way that it retains permissions relating to the original source, rather than your computer. Have a look at the properties / security settings on that file and compare them to another working file (doesn't need to be a powerpoint file - any document you can open with another programme will be fine). If you see a marked difference it may well be this rather than a virus.
 
Well, the date has now passed, and Windows 10 is no longer supported. Hopefully, the readers of this forum have done one of the many ways this issue can be handled. If not, do a YouTube search and a smorgasbord of solutions will be returned. What I want to mention is that I chose to use a debloated Windows from a debloater. There are many available options, e.g., Chris Titus Utilities (I used a product called Velotic, which also features AI to prevent your computer from overheating etc...

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