Question about nucleotides and phosphoric acid

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SUMMARY

The discussion clarifies the chemical terminology regarding the linkage of phosphoric acid to sugars in nucleotides. The correct term is "ester bond," not "ether bond," as the linkage involves the formation of a phosphoric ester through the dehydration reaction of a hydroxyl group. Participants emphasized that once the hydroxyl group reacts, it no longer exists, making the terminology critical for accurate scientific communication.

PREREQUISITES
  • Understanding of basic organic chemistry concepts, specifically ester and ether bonds.
  • Familiarity with nucleotides and their structural components.
  • Knowledge of dehydration reactions in organic chemistry.
  • Awareness of chemical terminology and nomenclature.
NEXT STEPS
  • Research the formation and properties of phosphoric esters in biochemistry.
  • Study the differences between ester and ether bonds in organic compounds.
  • Explore the role of hydroxyl groups in chemical reactions.
  • Examine the structure and function of nucleotides in biological systems.
USEFUL FOR

Chemistry students, biochemists, and anyone involved in molecular biology or organic chemistry who seeks to understand the precise terminology and concepts related to nucleotides and their chemical linkages.

physicisttobe
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Misplaced Schoolwork Thread -- Moved to the Schoolwork forums
Hi everyone!

Is this sentence correct?

"Phosphoric acid is linked to the hydroxyl groups of the sugars via ether bonds"

I would say yes, but in the solutions this phrase is wrong and I'm a little bit confused. I think that's correct, isn't it?
 
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Technically they’re esters. An ester is any linkage that has been formed through a hydroxyl by loss of a water molecule. The most familiar example is carboxylic esters, but in this case you have a phosphoric ester. In really old literature, you’ll occasionally see alkyl halides referred to as halide esters (e.g., butyl iodide would be butane hydriodic ester), reflecting the idea that they're formed from the dehydration reaction of the hydrogen halide with an alcohol.
 
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All right, thank you for your reply TeethWhitener!
So instead of ether bond there must be an ester bond, then it's correct.
I have mixed up the two.
 
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Perhaps that's nitpicking, but I don't like the idea of "being linked to the hydroxyl group". Hydroxyl group reacted and no longer exists, so nothing can be linked to it.
 
All right, thanks borek!
 

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