Replenish Gut Flora: Options Beyond Fecal Transplant

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Discussion Overview

The discussion centers on methods to replenish gut flora following antibiotic treatment, specifically exploring alternatives to fecal transplants. Participants consider the effectiveness of probiotics, dietary changes, and other potential solutions.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • Some participants express concern that antibiotics eliminate beneficial bacteria, questioning whether dietary changes and probiotics can effectively restore the gut microbiome.
  • One participant suggests that soil-based organisms might be a potential solution but notes a lack of scientific evidence to support this claim.
  • Another participant mentions that capsules of bacteria, presumably probiotics, can be obtained without a prescription but emphasizes the importance of consulting a doctor before self-treatment.
  • A participant raises the point that many probiotics are transient and do not colonize the gut, citing research that indicates probiotics may only temporarily alter gene expression in existing gut microbes.
  • There is a personal account of a participant who found success with a specific probiotic during antibiotic treatment, although they caution that individual experiences may vary and recommend consulting a doctor.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the effectiveness of probiotics or alternative methods for gut flora replenishment. There are competing views on the role of probiotics and the potential for other organisms to aid in recovery.

Contextual Notes

Some claims are based on personal experiences and anecdotal evidence, while others reference scientific studies. The discussion highlights the complexity of gut microbiome recovery and the variability in individual responses to different treatments.

Who May Find This Useful

This discussion may be of interest to individuals seeking alternatives to fecal transplants for gut flora restoration, healthcare professionals exploring treatment options, and researchers studying gut microbiome dynamics.

wywong
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Antibiotics often killed off good bacteria species in our guts. Are there any ways to replenish them, other than the unpleasant fecal transplant procedure?

A search on this topic mostly return recommendations on healthy diet and probiotics. I reckon these can only help surviving species, and those species that have been eradicated are gone for good. Or could their kin somehow re-colonize our guts?

Some suggest soil-based organisms, but I am unable to find any supporting scientific evidence.
 
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You can take capsules of bacteria, which in the US can be obtained from your pharmacist without a prescription. But, as always, ask your doctor before self treating since they know your history.
 
Do you mean those sold as probiotics? My understanding is that those bacteria strains are transient in our gut; they don't colonize. For example

The investigators showed that the probiotic product did not change the gut's overall bacterial composition, but instead altered gene expression patterns relevant to carbohydrate metabolism in the host's resident gut microbes.[14] These changes in the human fecal "metatranscriptome" were transient, confined only to the time of the probiotic consumption. Thus, if sustained benefit from a probiotic is desired, continued consumption is likely required.

from http://www.medscape.com/viewarticle/770468_3

Also those probiotics often contain only a few strains, which do not seem enough to make up the loss of the microbiome.
 
Your link doesn't work for me.

The type I took worked for me and the antibiotic I was on was meant to completely wipe out my bacteria, because I had an infection that would not go away, so I had to take the capsules daily, it was a 30 day course, like I said, talk to your doctor. This thread is closed as we cannot go into anything more specific.

Here is an explanation of when fecal transplantation would be considered.

http://www.hopkinsmedicine.org/gast...advanced_endoscopy/fecal_transplantation.html
 
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