Fecal Transplants to Cure Disease?

  • Context: Medical 
  • Thread starter Thread starter rhody
  • Start date Start date
  • Tags Tags
    Disease
Click For Summary

Discussion Overview

The discussion revolves around the use of fecal transplants as a potential treatment for various diseases, including asthma and multiple sclerosis (MS). Participants explore the implications of DIY fecal transplants, the scientific understanding of gut bacteria, and the challenges of medical acceptance of such treatments.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • Some participants highlight the personal story of Chris Gorski, who is considering performing a fecal transplant on his daughter, suggesting that this procedure may help with certain diseases.
  • There is mention of ongoing scientific research aimed at identifying beneficial gut bacteria that could combat diseases like diabetes and obesity.
  • Some participants express skepticism about the efficacy of fecal transplants for curing MS, indicating a belief that the evidence may not support such claims.
  • Others reference the use of fecal transplants in veterinary medicine for repopulating necessary bacteria after treatments like C. difficile, suggesting that the application in humans may be overreaching.
  • A few participants note the unusual nature of a study that includes DIY instructions for fecal transplants, raising questions about the medical community's stance on such practices.

Areas of Agreement / Disagreement

Participants generally express mixed views, with some supporting the idea of fecal transplants for certain conditions while others remain skeptical, particularly regarding the treatment of MS. There is no consensus on the overall efficacy or appropriateness of the procedure.

Contextual Notes

Limitations include the lack of comprehensive evidence supporting the use of fecal transplants for all proposed diseases, as well as the potential risks associated with DIY medical procedures.

rhody
Gold Member
Messages
680
Reaction score
3
Interesting article: Atlantic Monthly
If his four-year-old daughter gets sick again, Chris Gorski will take a drastic step. He will collect some of his own stool, strain it, and then transfer it into his daughter's body. This procedure -- known as a fecal transplant -- has been shown to help people like Chris's daughter Maya. Meanwhile, other patients and scientists hope that this bizarre transplant might work as medicine for a range of diseases, from asthma to MS.

and...

Gorski contacted the doctors at Mass General and begged them to see his daughter. No response. He tried other doctors around the country -- no luck. Then one gastroenterologist -- whose hospital had barred him from performing the operation on a child -- agreed to help. The doctor taught Gorski how to perform the procedure at home.

Now, Gorski says, "I'm getting my stool and blood tested to make sure that I don't carry any pathogens. That way I'll be prepared, if the time comes and I need to donate my bacteria to Maya."

Gorski's plan may sound medieval, but in fact he is at the forefront of a revolution. We are about to enter the era of living medicines. Scientists in labs around the country are racing to identify the thousands of bacteria that live in our gut, and to figure out which of these species help human beings fight off disease. Ideally, they will be able to pick out the bugs that help our bodies ward off diabetes, or obesity, or asthma.

But such treatments still shimmer in the future. In the meantime, the best approximation we've got is, well, crap. A healthy person's poop teems with bacteria that keep his or her body running smoothly. Some patients believe that they're sick, in part, because they're missing crucial species of bacteria. Medical studies show they may be right -- childhood asthma and Crohn's disease, for instance, appear to be related to a disruption of the gut.

and...

A few years ago, a team of Canadian doctors published a study of patients who tried the at-home transplants. The research paper is unusual in that it includes detailed instructions for performing the DIY medical procedure. It's as if -- with a wink and a nod -- the scientists are urging patients, especially those who have been turned away from hospitals, to operate on themselves.

It's as if modern medicine, has a deep aversion to this approach to treating a family member (with safeguards in place). I say let medical scientists test and vet it, then, let the chips (pun intended) fall where they may.

Rhody...
 
Biology news on Phys.org
berkeman said:
The "Similar Threads" links below show a thread about this from early 2011 with more info:

https://www.physicsforums.com/showthread.php?t=467647
Thanks berkeman,

Dimly in the recesses of my mind I must have been aware of it, but I do find it odd that on 01/27/2011 a similar story was released and this one on 01/25/2011 by slate.com. Probably just a coincidence, right ?

Rhody...
 
Re-establishing a healthy bacteria colony, I can believe. But curing MS I'm skeptical of.
 
Pythagorean said:
Re-establishing a healthy bacteria colony, I can believe. But curing MS I'm skeptical of.

I agree. I've heard of doing it to repopulate necessary bacteria after treating C. Diff., at least in veterinary settings, but this sounds like it's being stretched too far beyond what evidence supports.
 

Similar threads

Replies
11
Views
2K
Replies
1
Views
2K
  • · Replies 3 ·
Replies
3
Views
2K
  • · Replies 18 ·
Replies
18
Views
6K
Replies
4
Views
2K
  • · Replies 1 ·
Replies
1
Views
2K
Replies
6
Views
2K
  • · Replies 12 ·
Replies
12
Views
6K
  • · Replies 4 ·
Replies
4
Views
11K
  • · Replies 6 ·
Replies
6
Views
6K