Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

RNA Primers = Part of Okazaki fragments?

  1. Nov 17, 2013 #1
    Hi, I have a simple semantics question.

    I have been reading some literature that seems to consider RNA Primers as part of Okazaki fragments, but this should not be so because Okazaki Fragments by definition are just the DNA portions synthesized on the lagging strand. Any opinions/clarifications on this?
  2. jcsd
  3. Nov 18, 2013 #2
    As you probably know, each Okazaki fragment for the lagging DNA stand requires its own RNA primer, but if I understand your question, the RNA primers are not retained in the final DNA stand whereas the Okazaki fragments are.

    EDIT: It's possible that the name 'Okazaki fragment' may no longer apply once the RNA primer has been removed by DNA polymerase and the fragments joined by DNA ligase. At this point, it seems they are no longer fragments.
    Last edited: Nov 18, 2013
Know someone interested in this topic? Share this thread via Reddit, Google+, Twitter, or Facebook

Similar Discussions: RNA Primers = Part of Okazaki fragments?
  1. Designing primers (Replies: 2)

  2. Klenow Fragment (Replies: 3)

  3. RNA and Histones (Replies: 3)

  4. RNA interference (Replies: 2)