- #1
- 5,661
- 4,506
Open access.
https://www.nature.com/articles/s41586-021-03491-6
A more approachable synopsis at:
https://www.news-medical.net/news/2...ug-blocks-SARS-CoV-2-damage-in-the-lungs.aspx
Cheers,
Tom
Some Common Meds Block SARS-CoV-2 Attachment to Cells
Click For Summary
SUMMARY
Niclosamide and salinomycin effectively block SARS-CoV-2 attachment to cells and inhibit viral replication at both low and high doses. Clofazimine, while also effective, demonstrated a potency that was 10-fold less than that of niclosamide and salinomycin. All three drugs show promise in preventing viral production, making them significant candidates for further research in COVID-19 treatment.
PREREQUISITES- Understanding of antiviral mechanisms
- Familiarity with drug efficacy and potency comparisons
- Knowledge of SARS-CoV-2 viral replication processes
- Basic pharmacology of niclosamide, salinomycin, and clofazimine
- Research the antiviral properties of niclosamide in clinical settings
- Investigate the mechanisms of action of salinomycin against viral infections
- Explore the pharmacokinetics of clofazimine in respiratory diseases
- Review recent studies on drug repurposing for COVID-19 treatment
Researchers in virology, pharmacologists, and healthcare professionals focused on COVID-19 treatment strategies will benefit from this discussion.
Open access.
https://www.nature.com/articles/s41586-021-03491-6
A more approachable synopsis at:
https://www.news-medical.net/news/2...ug-blocks-SARS-CoV-2-damage-in-the-lungs.aspx
Cheers,
Tom
- #2
pinball1970
Gold Member
2025 Award
- 3,651
- 5,786
FYRTom.G said:
Science mag on line has a link on the front page to latest COVID publications