Spliceosome "cut and paste" introns and exons

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The spliceosome identifies splice sites on the RNA strand through specific nucleotide sequences in the mRNA that interact with particular protein factors. These sequences serve as signals that guide the spliceosome in accurately removing introns and joining exons. The complexity and precision of DNA/RNA protein synthesis are highlighted as fascinating aspects of molecular biology.
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How does the spliceosome know where to splice on the RNA strand? It will remove the introns and splice the exons together but how does it know where to slice?
 
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Thank You! The book you referenced is awesome. DNA/RNA protein synthesis is spooky amazing to me.
 
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Bob10 said:
Thank You! The book you referenced is awesome. DNA/RNA protein synthesis is spooky amazing to me.

Agreed!
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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