Stress hormones and limbic system?

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SUMMARY

The discussion centers on the effects of stress hormones, specifically cortisol and adrenaline, on the limbic system. Chronic elevation of cortisol negatively impacts the hypothalamus, leading to decreased CRH production and potential damage to hippocampal cells, which affects memory recall and the HPA axis. Prolonged exposure to stress hormones is linked to various health issues, including cognitive problems, diabetes, and depression, particularly when experienced during critical developmental periods. The conversation emphasizes the need for specificity in inquiries regarding the effects of stress hormones.

PREREQUISITES
  • Understanding of the HPA axis and its components
  • Knowledge of cortisol and adrenaline functions
  • Familiarity with the limbic system, particularly the hypothalamus and hippocampus
  • Awareness of the impact of chronic stress on mental health
NEXT STEPS
  • Research the role of the hypothalamus in cortisol regulation
  • Explore the relationship between chronic stress and hippocampal damage
  • Investigate the long-term effects of stress hormones on brain development
  • Study the correlation between prolonged stress exposure and specific diseases
USEFUL FOR

This discussion is beneficial for neuroscientists, psychologists, mental health professionals, and anyone interested in the physiological effects of stress on the brain and overall health.

petrushkagoogol
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What effect do stress hormones like cortisol and adrenaline have on the limbic system?
 
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petrushkagoogol said:
What effect do stress hormones like cortisol and adrenaline have on the limbic system?
Have you done any research on this yourself?
 
I know that the hypothalamus plays a role in the negative feedback of cortisol production. High levels of cortisol cause the hypothalamus to downregulate the CRH production of the hypothalamus. When cortisol levels are chronically elevated due to stressful events, the cells in the hippocampus can become damaged and result in weakened memory recall and negative feedback of the HPA axis. I think this has been found in schizophrenics and depressed patients.

http://www.nationalelfservice.net/cms/wp-content/uploads/2014/01/Stress_review.pdf
 
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Numerous effects occur. Are you asking about the mechanisms that take place throughout the brain and body during one normal event, or about what constant prolonged levels over a certain time period does to a developing or adult brain? There are numerous diseases that prolonged exposure has correlation with. Can you be more specific with your question?
 
Fervent Freyja said:
Numerous effects occur. Are you asking about the mechanisms that take place throughout the brain and body during one normal event, or about what constant prolonged levels over a certain time period does to a developing or adult brain? There are numerous diseases that prolonged exposure has correlation with. Can you be more specific with your question?

Effects of prolonged exposure....
 
There is a large difference in outcomes if this occurred in childhood development as a prolonged response to ritual trauma (where it can dramatically alter the structure of the brain) versus the stress accrued in middle adulthood crisis. Prolonged exposure is found to be very detrimental to health, this is correlated with far too many diseases and symptoms for me to list (cognitive problems, diabetes, cancers, depression, adrenal failure, thyroid dysfunction, hair loss, behavioral changes, compromised immune function, etc.). Can you, again, be more specific about what you want to know? What age range? Duration? Any diseases or symptoms that you want to know it is associated with?
 
And answer my question posted in #2
 
@petrushkagoogol please answer Phind's question about what research you have done yourself, we don't exist as an answers service but expect members to show some effort.
 
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petrushkagoogol said:
That tells us you found an article. Doesn't tell us you understand it or have in any way answered your own question. You are being very resistant to the forum rules. Not a good idea.
 
  • #11
The abstract states that the response of the higher brain is based on experience in cases of chronic stress.
 

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