Stress hormones and limbic system?

Click For Summary

Discussion Overview

The discussion centers on the effects of stress hormones, particularly cortisol and adrenaline, on the limbic system. Participants explore various aspects of this topic, including mechanisms, developmental impacts, and correlations with diseases, without arriving at a consensus.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • Some participants note that the hypothalamus is involved in the negative feedback of cortisol production, with chronic high levels potentially damaging hippocampal cells and affecting memory recall.
  • Others emphasize the need for specificity regarding the effects of stress hormones, questioning whether the inquiry pertains to acute events or prolonged exposure and its impact on brain development.
  • One participant highlights the significant differences in outcomes based on the timing of stress exposure, such as childhood versus middle adulthood, and lists various health issues correlated with prolonged stress exposure.
  • There are calls for participants to demonstrate their own research efforts rather than seeking answers without prior engagement with the topic.
  • A later reply mentions that the response of the higher brain is influenced by experiences related to chronic stress.

Areas of Agreement / Disagreement

Participants express differing views on the specific effects of stress hormones and the importance of context, such as age and duration of exposure. There is no consensus on the exact mechanisms or outcomes discussed.

Contextual Notes

Participants have not fully defined the parameters of their inquiries, such as the specific age ranges or symptoms they are interested in, which may limit the clarity of the discussion.

petrushkagoogol
Messages
28
Reaction score
4
What effect do stress hormones like cortisol and adrenaline have on the limbic system?
 
Biology news on Phys.org
petrushkagoogol said:
What effect do stress hormones like cortisol and adrenaline have on the limbic system?
Have you done any research on this yourself?
 
I know that the hypothalamus plays a role in the negative feedback of cortisol production. High levels of cortisol cause the hypothalamus to downregulate the CRH production of the hypothalamus. When cortisol levels are chronically elevated due to stressful events, the cells in the hippocampus can become damaged and result in weakened memory recall and negative feedback of the HPA axis. I think this has been found in schizophrenics and depressed patients.

http://www.nationalelfservice.net/cms/wp-content/uploads/2014/01/Stress_review.pdf
 
  • Like
Likes   Reactions: petrushkagoogol
Numerous effects occur. Are you asking about the mechanisms that take place throughout the brain and body during one normal event, or about what constant prolonged levels over a certain time period does to a developing or adult brain? There are numerous diseases that prolonged exposure has correlation with. Can you be more specific with your question?
 
Fervent Freyja said:
Numerous effects occur. Are you asking about the mechanisms that take place throughout the brain and body during one normal event, or about what constant prolonged levels over a certain time period does to a developing or adult brain? There are numerous diseases that prolonged exposure has correlation with. Can you be more specific with your question?

Effects of prolonged exposure....
 
There is a large difference in outcomes if this occurred in childhood development as a prolonged response to ritual trauma (where it can dramatically alter the structure of the brain) versus the stress accrued in middle adulthood crisis. Prolonged exposure is found to be very detrimental to health, this is correlated with far too many diseases and symptoms for me to list (cognitive problems, diabetes, cancers, depression, adrenal failure, thyroid dysfunction, hair loss, behavioral changes, compromised immune function, etc.). Can you, again, be more specific about what you want to know? What age range? Duration? Any diseases or symptoms that you want to know it is associated with?
 
And answer my question posted in #2
 
@petrushkagoogol please answer Phind's question about what research you have done yourself, we don't exist as an answers service but expect members to show some effort.
 
  • Like
Likes   Reactions: jim mcnamara and Pepper Mint
  • #10
petrushkagoogol said:
That tells us you found an article. Doesn't tell us you understand it or have in any way answered your own question. You are being very resistant to the forum rules. Not a good idea.
 
  • #11
The abstract states that the response of the higher brain is based on experience in cases of chronic stress.
 

Similar threads

  • · Replies 2 ·
Replies
2
Views
2K
  • · Replies 2 ·
Replies
2
Views
2K
  • · Replies 7 ·
Replies
7
Views
2K
  • · Replies 6 ·
Replies
6
Views
3K
  • · Replies 6 ·
Replies
6
Views
27K
  • · Replies 7 ·
Replies
7
Views
3K
  • · Replies 3 ·
Replies
3
Views
2K
  • · Replies 20 ·
Replies
20
Views
4K
  • · Replies 18 ·
Replies
18
Views
4K
  • · Replies 1 ·
Replies
1
Views
1K