What effect do stress hormones like cortisol and adrenaline have on the limbic system?
Have you done any research on this yourself?
I know that the hypothalamus plays a role in the negative feedback of cortisol production. High levels of cortisol cause the hypothalamus to downregulate the CRH production of the hypothalamus. When cortisol levels are chronically elevated due to stressful events, the cells in the hippocampus can become damaged and result in weakened memory recall and negative feedback of the HPA axis. I think this has been found in schizophrenics and depressed patients.
Numerous effects occur. Are you asking about the mechanisms that take place throughout the brain and body during one normal event, or about what constant prolonged levels over a certain time period does to a developing or adult brain? There are numerous diseases that prolonged exposure has correlation with. Can you be more specific with your question?
Effects of prolonged exposure.............
There is a large difference in outcomes if this occurred in childhood development as a prolonged response to ritual trauma (where it can dramatically alter the structure of the brain) versus the stress accrued in middle adulthood crisis. Prolonged exposure is found to be very detrimental to health, this is correlated with far too many diseases and symptoms for me to list (cognitive problems, diabetes, cancers, depression, adrenal failure, thyroid dysfunction, hair loss, behavioral changes, compromised immune function, etc.). Can you, again, be more specific about what you want to know? What age range? Duration? Any diseases or symptoms that you want to know it is associated with?
And answer my question posted in #2
@petrushkagoogol please answer Phind's question about what research you have done yourself, we don't exist as an answers service but expect members to show some effort.
That tells us you found an article. Doesn't tell us you understand it or have in any way answered your own question. You are being very resistant to the forum rules. Not a good idea.
The abstract states that the response of the higher brain is based on experience in cases of chronic stress.
Separate names with a comma.