Unresolved issues in computational physics are highlighted, particularly concerning NP-complete problems and the challenges posed by large data sets that complicate solving these problems within a finite time frame. The discussion references an article from Frontiers in Physics that explores these computational challenges, emphasizing the significance of the P versus NP problem in understanding the limitations of current computational methods in physics. The complexities of these issues suggest that advancements in computational techniques are necessary to address the intractability of certain physics problems.