Zona Pellucida: Digested or Not?

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SUMMARY

The zona pellucida is digested at the time of fertilization in humans, but it remains intact during the cleavage process to prevent abnormal implantation. Five days post-fertilization, the blastocyst undergoes zona hatching, leading to the degeneration of the zona pellucida, which is replaced by trophoblastic cells. This process is accurately described in the Wikipedia article on zona pellucida, which clarifies common misconceptions found in textbooks that may oversimplify the topic.

PREREQUISITES
  • Understanding of human embryology
  • Familiarity with the fertilization process
  • Knowledge of blastocyst development
  • Basic concepts of zona pellucida function
NEXT STEPS
  • Read the Wikipedia article on zona pellucida for a comprehensive overview
  • Explore the mechanisms of zona hatching in human embryos
  • Investigate the role of trophoblastic cells in implantation
  • Examine differences in zona pellucida function across species, particularly between humans and mice
USEFUL FOR

Students of embryology, reproductive biologists, and anyone studying human fertilization and early development processes.

gracy
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My textbook says zona pellucida is digested at the time of fertilization but then it mentions that zona pellucida remains intact throughout the cleavage process to avoid /prevent implantation at abnormal places. If zona pellucida is digested at the time of fertilization then how it reappears during cleavage process?
 
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I'm confused -- it appears you are missing an assumption but let's start with assuming we are talking about humans:

From Wikipedia
In humans, five days after the fertilization, the blastocyst performs zona hatching; the zona pellucida degenerates and decomposes, to be replaced by the underlying layer of trophoblastic cells.

Which is somewhat like what you are describing.

Check out this article and follow the links. Then come back with what did not make sense.
https://en.wikipedia.org/wiki/Zona_pellucida

I believe the Wiki article to be pretty good, and unless your textbook is using an older pure mouse model, we should all be on the same page now. Sometimes textbook authors simplify or gloss over something they think you should already know. But they seem not to notice they never have covered it. Upper level math books often are the worst case for this IMO. So, get used to it.
 
It is probably only referring to the sperms actual point of entry being "digested".
 
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