Recent content by Soaring Crane

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    Biology Genetics: Understanding the Base Sequence of Messenger RNA

    Therefore, as indicated from my first post, mRNA sequence VII, 5'-UCGUCGACGAUGAUCAUCGGCUACUCGA-3', results when sequence III 3′-AGCAGCTGCTACTAGTAGCCGATGAGCT-5' is the template strand and sequence II (Strand A) is the coding, or non-template, strand (5′-TCGTCGACGATGATCATCGGCTACTCGA-3'). Is...
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    Biology Genetics: Understanding the Base Sequence of Messenger RNA

    If I use 3′-AGCAGCTGCTACTAGTAGCCGATGAGCT-5' as the template strand and rules T = A and A = U, then would not the mRNA strand be: --------5'-UCGUCGACGAUGAUCAUCGGCUACUCGA-3'? [1] From V. in the example, the above [1] does not match: --------5’-UCGAGUAGCCGAUGAUCAUCGUCGACGA-3’. I apologize for...
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    Biology Genetics: Understanding the Base Sequence of Messenger RNA

    Dear Ygggdrasil, If you look at the coding, or non-template, strand 5’-TCGTCGACGATGATCATCGGCTACTCGA-3’, how is this the same sequence as the mRNA strand in V (with exception of substituting T with U), 5’-UCGAGUAGCCGAUGAUCAUCGUCGACGA-3’?Thank you for any clarification.
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    Biology Genetics: Understanding the Base Sequence of Messenger RNA

    Homework Statement [/B] I am reviewing an example on the basics of the genetic code; this example is listed at the bottom of the following webpage: https://www.atdbio.com/content/14/Transcription-Translation-and-Replication.I have produced the example below and added Roman numbers to better...
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    Transgenic Mice Models and Integration of DNA

    I have no experience working with mice models, but why, for example, in pronuclear injection (or even other methods of transgenesis), is the injected gene of interest randomly integrated? In other words, why would the integration site of the DNA not be known or in a targeted region? I apologize...
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    Survival Analysis: Two Degree of Freedom Joint Test?

    In survival analyses, such as proportional hazards models, can you carry out a two degree of freedom joint, or likelihood ratio test, in which the full model is compared to a reduced model that is missing two regression coefficients (or where two regression coefficients are set to 0 in...
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    Xenopus and Zebrafish as Models of Human Disease

    For zebrafish and Xenopus, are there currently any effective gene knockout strategies? From literature, these two organisms have effective gene knockdown strategies in practice. Thanks for any help.
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    Exome Sequencing: Chip vs. Sequencing

    Is there a difference between an exome chip and exome sequencing? Thank you.
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    Can Hedges' g be greater than 1 for paired t-tests?

    If you have a data set comprised of test scores before studying (G1) and a data set comprised of test scores after studying (G2), formula would read as: g = (mean_G1 - mean_G2)/(mean of standard deviation_G1 and standard deviation_G2). Thank you.
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    Can Hedges' g be greater than 1 for paired t-tests?

    Can Hedges' g (effect size) for a paired t-test be greater than 1 if the following is the formula for g? g = (mean_1 - mean_2)/(average standard deviation of the two variables) Thank you.
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    Hemoglobin S Trait: Healthy Carrier?

    Thanks, epenguin. Yes, they are protected from malaria?
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    Hemoglobin S Trait: Healthy Carrier?

    If a person is a carrier for sickle cell disease or has hemoglobin AS, then does this mean that the carrier is not affected by hemoglobinopathy? (He/she is normal/healthy?) Thank you.
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    Measures of Variability/Central Tendency For Certain Categories

    Homework Statement Suppose that I have the following groups/categories with how each is measured next to them: Response to light – measured on a scale of 1 to 4 HDL levels – continuous value from 1 to 100 Smoker status - smoker or non-smoker The question is as follows: What are...
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    Formula For Confidence Interval of Two Samples With Unequal Variances

    ImaLooser, I apologize. It would be the confidence interval for the mean difference (difference of the sample means) in the case where the population variances are unknown. For example, I know the formula for calulating the t-score for the t-test with unequal variances: t = (mean...
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    Formula For Confidence Interval of Two Samples With Unequal Variances

    Are there any online sources that would note (and define all variables, especially on how to calculate standard error) in the formula for calculating the confidence interval, a complement to the t-test, of two independent samples with unequal variances? (I want to see exactly how...
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