To calculate the percentage of uncertainty in momentum, one must divide the change in momentum (delta p) by the momentum (p) and multiply by 100%. The uncertainty in momentum should not equal the momentum itself; otherwise, it results in a misleading 100% uncertainty. The discussion centers on applying Heisenberg's Uncertainty Principle, with specific values for the uncertainty in position and kinetic energy of an electron. Correct calculations using the appropriate formulas should yield a percentage uncertainty significantly less than 1%. The importance of using the correct formulas and values is emphasized to avoid confusion in results.