- #1
nokia8650
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I was struggling with interpreting the following pedigree diagram:
http://img245.imageshack.us/img245/715/photoon20100411at2211.jpg
I can see from the diagram that only females seem to be capable of transmitting the disease - not males - this lead me to believe it is X-linked. In addition, I noted that EVERY offspring of an affected female is also affected; leading me to believe it is dominant. This lead to me thinking the condition was inherited in an x-linked dominant manner. However, this would not explain why affected males (who would in my model have the dominant disorder on their X chromosome) do not pass on the condition to their female offspring.
Any help is greatly appreciated.. thanks!
http://img245.imageshack.us/img245/715/photoon20100411at2211.jpg
I can see from the diagram that only females seem to be capable of transmitting the disease - not males - this lead me to believe it is X-linked. In addition, I noted that EVERY offspring of an affected female is also affected; leading me to believe it is dominant. This lead to me thinking the condition was inherited in an x-linked dominant manner. However, this would not explain why affected males (who would in my model have the dominant disorder on their X chromosome) do not pass on the condition to their female offspring.
Any help is greatly appreciated.. thanks!
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