Thank you! But I'm dense. Can you clarify a little more? I was reading how Sidney Farber injected almost comatose kids with aminopterin and they got out of bed and played (for a few months). Is it just that there is so much folate in a body--even in the presence of an antifolate-- that the...
How do antifolates work re leukemia? I don't understand how healthy blood cells can get enough folate to mature when the same body's cancerous blast cells are being starved of it. Without folate, an otherwise healthy person gets anemic. How does this not apply to cancer patients? Can someone...