Stimulating neurons via magnetic fields

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Discussion Overview

The discussion revolves around the use of transcranial magnetic stimulation (TMS) to stimulate neurons in the brain through magnetic pulses. Participants explore the potential applications, implications, and risks associated with this technique, as well as its current state in research and clinical practice.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • Some participants express optimism about the potential of TMS to "rewire the brain" and simulate physiological processes related to neural growth.
  • Concerns are raised about the safety of TMS, with participants noting that high-frequency stimulation can cause seizures and that lower frequencies may disrupt normal neuronal firing.
  • References to studies indicate that while results from TMS are inconsistent, there have been improvements in conditions such as depression and bipolar disorder in some patients.
  • Participants acknowledge the current limitations of TMS technology, comparing its early development to that of the first transistors, suggesting there is room for significant improvement.

Areas of Agreement / Disagreement

Participants express a mix of optimism and concern regarding TMS, indicating that while some see potential benefits, others highlight significant risks and limitations. There is no consensus on the overall efficacy or safety of the technique.

Contextual Notes

Participants note that the results of TMS studies are still inconsistent, and there are unresolved questions about the physiological mechanisms involved in its effects on mental processes.

saltydog
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I ran across this article in "Newsweek-Next Frontiers" about stimulating neurons directly by firing large magnetic pulses to specific locations in the brain:
By projecting an electrical charge through the skull, they can now flick neurons on and off without ever breaking the skin . . . The technique, known as transcranial magnetic stimulation, or TMS, uses a $30,000 contraption to fire a powerful magnetic pulse into the cranium, creating an electric charge that activates brain cells.

Address: http://www.msnbc.msn.com/id/9557716/site/newsweek/

Well, I can imagine a much more "accurate" device which can affect individual neurons or "local" populations of neurons. Surely if one could "modulate" the pulses in such a way to simulate the physiological process involved with real neural growth, then indeed I think we would be achieving what the article declared "Re-wiring the brain". Big 'if' though. We really don't even know how physiological processes give rise to mental ones, not exactly anyway. But still, I somewhat suspect this is the beginnings of something . . . wonderful. :smile:
 
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Sounds dangerous.
 
jammieg said:
Sounds dangerous.
It could well be. At high frequencies it causes seizures, which means at lower frequencies it probably works by disorganizing neuronal firing as well.

HMI World | Around Harvard
Address:http://hmiworld.org/hmi/current/around_brain.html

It seems in all cases to be temporary if it works at all.
 
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zoobyshoe said:
It could well be. At high frequencies it causes seizures, which means at lower frequencies it probably works by disorganizing neuronal firing as well.

HMI World | Around Harvard
Address:http://hmiworld.org/hmi/current/around_brain.html

It seems in all cases to be temporary if it works at all.

Thanks for the ref Zoobyshoe. This is a quote:

Although results are still inconsistent, the news from what now amounts to a large number of controlled studies is getting better. For example, in one study, high-frequency TMS directed at the left prefrontal cortex combined with low-frequency TMS to the right prefrontal cortex improved depression in patients who had not responded to drugs. Researchers have also found TMS helpful as a weekly maintenance treatment for adults with bipolar depression who were taking lithium. And interestingly, high-frequency TMS to the right prefrontal cortex may improve symptoms of bipolar mania.

Yea, I know we're still in the middle-ages with this. You know what the first transistor looked like? We made improvements didnt' we. :smile:
 
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