Who Won the 2020 Nobel Prize in Chemistry?

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SUMMARY

The 2020 Nobel Prize in Chemistry was awarded to biochemist Jennifer A. Doudna and microbiologist Emmanuelle Charpentier for their pioneering work on the CRISPR-Cas9 gene-editing technology. Despite significant contributions, researcher Pavel Siksnys was not awarded, as his role in the discovery has often been overlooked. The Nobel Prize's advanced information PDF highlights that Siksnys's findings on the CRISPR-Cas system in Streptococcus thermophilus paralleled those of Doudna and Charpentier, particularly in the mechanisms of Cas9 cleavage and the importance of crRNA, although he did not recognize the role of tracrRNA in sequence-specific cleavage.

PREREQUISITES
  • Understanding of CRISPR-Cas9 technology
  • Familiarity with molecular biology concepts
  • Knowledge of gene editing techniques
  • Awareness of the significance of RNA in genetic processes
NEXT STEPS
  • Research the mechanisms of CRISPR-Cas9 gene editing
  • Explore the role of tracrRNA in CRISPR technology
  • Investigate the contributions of Pavel Siksnys to CRISPR research
  • Watch the documentary "Human Nature" for a non-technical overview of CRISPR
USEFUL FOR

Researchers, molecular biologists, and anyone interested in the advancements of gene editing technologies, particularly those studying the CRISPR-Cas9 system and its applications in biotechnology.

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TL;DR
The Nobel Prize in Chemistry 2020 was awarded jointly to Emmanuelle Charpentier and Jennifer A. Doudna "for the development of a method for genome editing."
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Chemistry news on Phys.org
No prize for Siksnys?
 
because his part in the discovery of CRISPR often has been overlooked
crispr-researcher-wins-spotlight]From a 2018 article[/url] - about a prize awarded to him and the two (now) Nobel Prize winners.
Nature has a similar article
 
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biochemist Jennifer A. Doudna(below left) and microbiologist Emmanuelle Charpentier (below right):

Screen Shot 2020-10-07 at 11.06.53 PM.png
 
Netflix "Human Nature" I though was a good intro (non-tech) documentary on CRISPR.
 
atyy said:
No prize for Siksnys?

Here's what the Nobel Prize website's advanced infomation PDF has to say about Siksnys's work:
Similar findings were also published in another report using the related CRISPR-Cas system in Streptococcus thermophilus. As in Charpentier and Doudna’s work, this report also demonstrated that Cas9 cleaves within the protospacer, that cleavage specificity is directed by the crRNA sequence, and that the two nuclease domains within Cas9, each cleave one strand. However, the researchers did not notice the crucial importance of tracrRNA for sequence-specific cleavage of target DNA [29].
https://www.nobelprize.org/uploads/2020/10/advanced-chemistryprize2020.pdf
 
Another couple of biologists win the Chemistry Prize.
 
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