After translation, what determines the fate of mRNA molecules?

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Discussion Overview

The discussion focuses on the fate of mRNA molecules after translation, exploring whether they are degraded or can be reused for further translation. The scope includes biological mechanisms and the role of untranslated regions in determining mRNA stability and translational efficiency.

Discussion Character

  • Exploratory, Technical explanation, Conceptual clarification

Main Points Raised

  • Some participants propose that after translation, mRNA can either be retranslated by ribosomes or degraded, with untranslated regions influencing these outcomes.
  • One participant likens mRNA to a recipe for protein synthesis, emphasizing its role in guiding the translation process.
  • Another participant notes that the half-life of mRNA is variable, with some mRNAs persisting longer than others, depending on their specific untranslated regions.

Areas of Agreement / Disagreement

Participants generally agree that mRNA can be either degraded or reused, but they present varying details about the mechanisms and factors influencing these processes. No consensus on the specifics is reached.

Contextual Notes

The discussion highlights the dependence on untranslated regions for mRNA stability and translation, but does not resolve the implications of these factors or the exact mechanisms involved.

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What happens to mRNA's after translation. Do they get degraded?
 
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They can either be rebound by ribosomes and translated again or degraded. Sequences in the untranslated regions of the RNA control the extent to which certain mRNAs get retranslated or degraded.
 
the mRNA can be then brought to the ribosome and then with the help of tRNA to help make a protein. Thnk of the mRNA as a recipe to make a protein.
 
As Ygggdrasil says, mRNA molecules have a half life determined by the untranslated regions. Every mRNA is different. Some hang around for ages, others a rapidly degraded.
 

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