AS Biology - glycosis homework help

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SUMMARY

The discussion centers on the enzymatic regulation of glycolysis, specifically focusing on Hexokinase, Phosphofructokinase, and Pyruvate Kinase. Participants emphasize the importance of understanding both intrinsic and extrinsic regulation of these enzymes in the context of glycolysis. A reference to a biochemistry textbook is provided for further reading, highlighting the complexity and relevance of these concepts in broader biological contexts, such as diabetes.

PREREQUISITES
  • Understanding of glycolysis and its metabolic pathways
  • Knowledge of enzyme kinetics and regulation
  • Familiarity with intrinsic and extrinsic regulatory mechanisms
  • Basic biochemistry concepts related to metabolism
NEXT STEPS
  • Study the role of Hexokinase in glycolysis and its regulatory mechanisms
  • Research Phosphofructokinase and its significance as a key regulatory enzyme
  • Examine the function of Pyruvate Kinase and its impact on metabolic pathways
  • Explore the relationship between glycolysis regulation and diabetes management
USEFUL FOR

Students studying AS Biology, educators teaching metabolic pathways, and individuals interested in the biochemical regulation of metabolism.

Quadpatt
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Hi,
I'm really stuck on this part of my AS biology homework.

With reference to theenzymes catalysing the stages of glycolysis, explain how their activity can beaffected. Consider in your discussion if this is a form of intrinsic regulationor extrinsic regulation.

1) Hexokinase:

2) Phosphofructokinase:

3) Pyruvate kinase:

I understand these enzymes have a role in converting and regulation but I can't seem to find any information that I can understand. Any help on this would be greatly appreciated!

Thank you
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Most biochemistry textbooks will have a lot of information on this subject. For example, see https://www.ncbi.nlm.nih.gov/books/NBK22395/
 
OMG this is an AS level question? When I did a biochemistry degree, mynah mynah, most of this wasn't in it - in fact most of it wasn't known!

I am in two minds whether this is just cramming ever more stuff into school courses, or whether on the other hand deserves its place as rationalisation, more rational biology with general principles of feedback. Needing important illustrations or examples, which are also relevant to what anyone's general knowledge of things they will need to know later, e.g. about diabetes, and thus also relevant to people later not pursuing biological science as a speciality.
 

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