Based on the very basic understanding on enzymes I have gained from Year 12 Biology and Chemistry, I don't undesrtand why the enzymes specific shape also helps the reverse reaction. I guess my trouble would be due to the simplified diagrams I've seen from Biology, where only the forward reaction is shown to be catalysed. So if anyone has any explanations or links, that would be great. Also, a side question, does anyone have a link that compares organic and artificial catalysts; I've heard that enzymes are ridiculously more effective than standard artificial catalysts, but I can't really find what I'm looking for on the interenet. What do you compare? Is it the Turn Over Number? Anyway, any clarification would be greatly appreciated.