Biggest Breakthroughs in Biology and Neuroscience in 2023

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SUMMARY

The forum discussion highlights significant breakthroughs in biology and neuroscience for 2023, including advancements in understanding consciousness and the evolution of microbiomes. A notable development is rBIO's innovative approach to producing biosimilar insulin using custom-made bacteria, which promises to double the yield compared to current methods. Additionally, the discussion emphasizes a paradigm shift in cancer treatment, focusing on genetic profiles rather than organ-specific targeting, leading to revolutionary new therapies in molecular genetics.

PREREQUISITES
  • Understanding of molecular genetics and its implications in medicine
  • Familiarity with biosimilars and their role in biotechnology
  • Knowledge of cancer genetics and targeted therapies
  • Awareness of microbiome research and its evolutionary aspects
NEXT STEPS
  • Research the latest developments in biosimilar insulin production techniques
  • Explore the impact of molecular genetics on cancer treatment strategies
  • Investigate the role of microbiomes in human health and disease
  • Study the implications of consciousness research in biological sciences
USEFUL FOR

Biologists, biotechnologists, medical researchers, and healthcare professionals interested in the latest advancements in biology and neuroscience, particularly in the areas of genetics, biotechnology, and therapeutic innovations.

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Covers:
- An investigation of consciousness
- Microbiomes evolve with us
- How life keeps time

 
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Biology news on Phys.org
Where have all the flowers gone?
Long time passing...



No biologists on PF?
 
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jedishrfu said:
Where have all the flowers gone?
Long time passing...



No biologists on PF?

I have not got round to watching it but I will.

When I see "consciousness" in something relating to Biology, I always get the feeling some woo may be coming my way, so that first title probably delayed my watching.
 
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One biotech startup, rBIO of Houston, is aiming to make insulin more affordable by producing a copycat version of the drug—known as a biosimilar. It’s not the only company developing biosimilar insulin, but it says it has invented a new process to do so using custom-made bacteria.

CEO Cameron Owen says his company has created novel strains of bacteria that can produce insulin at twice the yield than is currently possible. Thursday, rBIO announced it had completed lab tests of its biosimilar insulin to determine that it is structurally and functionally similar to a brand-name one. It plans to begin a clinical trial later this year to determine whether its insulin works as well as a product already on the market.
https://www.wired.com/story/cheap-insulin-biosimilar-rbio/

https://www.sdbj.com/technology/rbio-succeeds-biomanufacturing-insulin/

Related
https://wyss.harvard.edu/news/designing-more-useful-bacteria/
 
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Greg Bernhardt said:
@Laroxe and @Ygggdrasil do you have any additional great breakthroughs for the year to list?
My personal favourite would be in the effects of our changed understanding of genetics, idea around how genes work were not only wrong, they had become fossilised. The breakthroughs in molecular genetics are what has lead to an explosion of new therapies in medicine which has been described as a revolution, the new "biologic" approaches will lead to massive changes in our understanding of health and disease and we are only at the start of these changes.
 
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On that line, what I tell people when the topic comes up is that the drug companies used to target a specific type of cancer (lung, cervical, skin, etc.) but they have discovered that they often need to target cancers genetically instead. Drugs that didn't seem to work well in a particular organ, can work very well for a specific type of genetic profile.

Disclaimer: this is not my field of study, I just try to be informed as much as possible. :oldwink:
 
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Can't say I'm Too excited about 2023 developments in biology.
Nothing very earth shaking or surprising. I'm waiting for next year.

The new stuff seems like a continuation of developments from previous years.

The most significant thing to me is the continuing climate crisis. Although it is more appreciated now than before, its too late for easy fixes.
Our children will have to deal with the results of this decades long distraction put on by big industries. Many will die. Many species will go extinct. Ecosystems will be F*cked.
Interesting times!
 
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