Calculate Pressure Drop of Air Across an Opening

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Futsal1st
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How do I determine the pressure drop of air across an opening? For example if I have 3,000 L/s (3 m3/s) and an opening of 8.4 m2 I know the velocity is 0.4 m/s. If the free area is 80%, the velocity increases to 0.45 m/s. What I'd like to cal is the pressure drop in each case.

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Sorry 'bout that.

Its a car park roller door that has small openings (almost rectangular)about 5mm high and 50mm long. It acts like a perforated panel between the outdoor and the car park.