Campbell and Reece 8th edition Cell Biology

[mishrashubham]

sorry about then

“A diploid embryo that is homozygous for a large deletion (or has a single Xchromosome with a large deletion, in a male) is usually missing a number ofessential genes, a condition that is ordinarily lethal.”
What does “A diploid embryo that is homozygous for a large deletion” mean?

thank you

These are pretty basic terms. You should try to look them up yourself on the internet first. BTW you should be well aware of these terms if you are studying university level biology.


Anyways; what the text is trying to say is that if a diploid embryo i.e. having a pair of each chromosome, is homozygous for a large deletion i.e. the deletion of a specific portion exists in both of the chromosomes of a homologous pair, it would not possesses any of the genes which were deleted and hence would face the consequences if they turn out to be essential. In case of males, they cannot rely on the other X chromosome if one suffers a deletion since they have only one X chromosomes.