Exactly what do you mean by "closed form solution"? Since a limits of integration are numbers, the integral is, of course, a single number, which is about as "closed form" as you can get! But I expect that you are asking about a method of finding that number, which is a different matter.
As jedishrfu said, seeing that [itex]x^2+ y^2[/itex], I would try polar coordinates. Of course, the fact that the region of integration is a rectangle rather than a disk complicates things!
As the "[itex]\theta[/itex]" line sweeps up from the x-axis ([itex]\theta= 0[/itex]) it first touches the rectangle at (2, 3) (slope 3/2), then at the point (2, 4) (slope 2), then (1, 3) (slope 3), and finally at (1, 4) (slope 4). That gives three intervals, [itex]\theta= arctan(3/2)[/itex] to [itex]arctan(2)[/itex], [itex]\theta= arctan(2)[/itex] to [itex]arctan(3)[/itex], and [itex]\theta= arctan(3)[/itex] to [itex]arctan(4)[/itex] on which the ray enters and leaves the rectangle through different edges.
For [itex]\theta= arctan(3/2)[/itex] to [itex]arctan(2)[/itex], the ray enters the rectangle through the bottom, [itex]y= r sin(\theta)= 3[/itex] (so [itex]r= 3/sin(\theta)= 3 csc(\theta)[/itex]) and leaves through the right side, [itex]x= rcos(\theta)= 2[/itex] (so [itex]r= 2/cos(\theta)=2 sec(\theta)[/itex]. That integral will be
[tex]\int_{arctan(3/2)}^{arctan(2)}\int_{3csc(\theta)}^{2sec(\theta)}\sqrt{1+4r^2} rdrd\theta[/tex].
For [itex]\theta= arctan(2)[/itex] to [itex]arctan(3)[/itex], the ray enters the rectangle through the bottom and leaves through top, [itex]y= r sin(\theta)= 4[/itex] (so [itex]r= 4/sin(\theta)= 4 csc(\theta)[/itex]). That integral will be
[tex]\int_{arctan(2)}^{arctan(3)}\int_{3csc(\theta)}^{4csc(\theta)}\sqrt{1+4r^2} rdrd\theta[/tex].
Finally, for [itex]\theta= arctan(3)[/itex] to [itex]arctan(4)[/itex], the ray enters the rectangle through the left edge, [itex]x= r cos(\theta)= 1[/itex] (so [itex]r= 1/cos(\theta)= sec(\theta)[/itex]). That integral will be
[tex]\int_{arctan(3)}^{arctan(4)}\int_{3sec(\theta)}^{4csc(\theta)}\sqrt{1+4r^2} rdrd\theta[/tex].
Now, can you do those integrals? Would you consider that "closed form"?