Can You Become Immune to Mosquito Bites?

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The discussion centers on the relationship between mosquito bites and immune responses, drawing a connection to the low allergy rates among the Amish. A personal account details the experience of building a sturdy shed over nine weeks, during which the individual faced intense mosquito exposure, resulting in numerous bites. Initially, the bites caused significant itching and welts, but after five weeks, the immune response diminished, leading to a notable reduction in reactions over the following years. This individual observed that while they still feel mosquito bites, they no longer experience welts, suggesting a form of acquired immunity. The conversation touches on the idea of developing tolerance to mosquito bites over time, contrasting personal experiences with those of others, including the mention of Skeeter Syndrome in children. The discussion highlights the complexities of immune reactions to insect bites and the potential for tolerance development.
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What happened to me in my backyard 25 years ago.
I was just reading a Washington Post story about the low incidence of allergies among the Amish. It reminded me of a story I have never "published" but is worth knowing - if only for better understanding allergies.

It happen about 25 years ago. I had just bought a new home and the winter started out with a few winter storms that had left well over two feet of snow on my roof. A very wet snowfall was in the forecast, so I went up on the roof and cleared it of snow.

When I returned home from work the next day, my house was fine - but a metal shed in my backyard was flattened. So, I recovered a few easy-to-get-to items and left the rest as a Spring project. The replacement would be something very sturdy that would survive the kind of neglect that I visited on it predecessor. A survey of the pre-fab market showed roofs supported by 2x3 and metal no stronger than what had been demolished.

So my the new shed would be of concrete footings and pressure-treated wood of my own design. Overall, there were eight vertical 4x4 posts bolted to other 2x8 members. The roof would be Gambrel in form using a combination of 2x4's, 2x8', and 2x10's. If this thing ever floats away, it will float away as a single piece.

It shares the same 16' x 16' foot print of it predecessor - adjacent to a swamp. So for about 9 weeks that spring, I worked several hours a day, several days a week until the shed was finished.

During that time, my exposure to mosquitoes was intense - with dozens of bites each day. I was generating enough sweat that bug sprays were ineffective. Citronella flames and bug zappers helped, but not much. As a kid, I wondered how the Indians ever put up with these little monsters and now more than ever I wondered again - but not for the full 9 weeks required to complete the shed.

After 5 weeks, there was no more itching and there were no more welts. And it wasn't until then that I realized that all the worse things about a mosquito bites (excluding West Nile Virus and EEE) are actually immune reactions.

This "immunity" (or actually a reduction in immunity) to mosquitoes remained solid for 7 years. Since then, mosquitoes sometimes cause me a short minor itch - but to this day, no welts and nothing lasting longer than a couple of minutes.

I still notice some mosquitoes and sometimes feel the bite. But except when they form dense clouds, I am able to ignore them.

Some years later I received allergy shots to reduce my reaction to a dozen other allergens. I suggested that the clinic also offer shots against mosquito bites. The doctor provided a quick "no". That's understandable. I'm sure that he would prefer for his patients simply avoid those little disease carriers.
 
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My experience is similar. Growing up in the US midwest, I got many, many mosquito bites. Then I spent time camping in Wisconsin and Minnesota, where they are everywhere. Now, 40-50 years later, I still get bitten, but no welts.
 
Hmm. Bitten so, so many times in India yet I still get huge welts every time. Though maybe since I am in India on-and-off the "downtime" between getting bitten by mosquitoes frequently stops me developing some sort of immunity. Or it takes a longer time to develop an immunity than 13 years.

Very interesting nonetheless.
 
I've lived in WI my entire life and haven't seemed to build any tolerance lol. I try to avoid as much as I can, so I'm not interested in building tolerance by subjecting myself to dozens of bites a day. :eek:

Somewhat related is that children can sometimes get a condition called Skeeter Syndrome, and can build tolerance over time with repeated bites

https://my.clevelandclinic.org/health/diseases/23289-skeeter-syndrome
 
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