Can You Create These Custom Pyrazole Derivatives?

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The discussion centers on a variety of chemical compounds, primarily focusing on various derivatives of pyrazole and imidazole, along with their respective chemical identifiers (CAS numbers). Key topics include the synthesis, applications, and properties of these compounds, which are often used in pharmaceuticals and agrochemicals. The conversation highlights specific derivatives such as 5-Amino-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester and its various halogenated forms, reflecting on their potential biological activities. Additionally, there is mention of the importance of structural modifications in enhancing the efficacy and selectivity of these compounds in medicinal chemistry. The dialogue emphasizes the relevance of these substances in ongoing research and development within the field.
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1- bromopyrrolidine-2,5-dione 128-08-5
2- (4-nitrophenyl)hydrazine hydrochloride 636-99-7
3- 2-methyl-3-nitrobenzoic acid 1975-50-4
4- 4-nitro-1H-imidazole 3034-38-6
5- 1H-pyrazole-4,5-dicarboxylic acid hydrate
6- 5-Methyl-3H-imidazole-4-carboxylic acid ethyl ester 51605-32-4
7- 2-Bromo-5-methyl-4H-imidazole-4-carboxylic acid ethyl ester 95470-42-1
8- 5-Amino-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester 866837-96-9
9- 2,5-Dinitro-1H-imidazole 5213-49-0
10- 2-Chloro-5-nitro-1H-imidazole 57531-37-0
11- 5-Amino-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester HCl Salt 70500-80-0
12- 5-Amino-1-(2-chloro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester HCl Salt 14678-86-5
13- 5-Amino-1-p-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester 15001-11-3
14- 1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride 72287-26-4
15- 3H-Imidazole-4-carboxylic acid 1072-84-0
16- 1H-Imidazole-4,5-dicarboxylic acid 570-22-9
17- Thionicotinamide 4621-66-3
18- 4-Chloro-thiobenzamide 2521-24-6
19- isoindolin-1-one 480-91-1‘
20- methyl 2-methyl-3-nitrobenzoate 59382-59-1
21- methyl 2-methyl-5-nitrobenzoate 77324-87-9
22- 6-nitroisoindolin-1-one 110568-64-4
23- methyl 5-bromo-2-methyl-3-nitrobenzoate 220514-28-3
24- 4-nitroisoindolin-1-one 366452-97-3 552330-86-6 675109-26-9 816-27-3
25- ethyl 2-ethoxy-2-iminoacetate hydrochloride 55149-83-2
26- ethyl 5-aminothiazole-4-carboxylate 18903-18-9 1013-88-3
27- diphenylmethanimine hydrochloride 5319-67-5
28- Tris(dibenzylideneacetone)dipalladium 52409-22-0
29- 5-Amino-1-(2-chloro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester 14678-86-5
30- 5-Chloro-1-(2-chloro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester 121716-34-5
31- 5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester 16078-71-0
32- 5-Chloro-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester 98534-76-0
33- 5-Bromo-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester 98534-71-5
34- 5-Cyano-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester 98476-09-6
35- 5-Amino-1-p-tolyl-1H-pyrazole-3-carboxylic acid ethyl ester 15001-11-3
36- 5-Chloro-1-p-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester
37- 5-Bromo-1-p-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester 959578-19-9
38- 5-Cyano-1-p-tolyl-1H-pyrazole-4-carboxylic acid ethyl ester 98476-29-0
39- 5-Amino-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 31037-02-2
40- 5-Chloro-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 56984-32-8
41- 5-Bromo-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 105486-72-4
42- 5-Cyano-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester 33090-55-0
43- 5-Amino-1-(2-chloro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester 866838-00-8
44- 5-Chloro-1-(2-chloro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester
45- 5-Bromo-1-(2-chloro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester
46- 1-(2-Chloro-phenyl)-5-cyano-1H-pyrazole-3-carboxylic acid ethyl ester
47- 5-Amino-4-bromo-1-(2-chloro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester
48- methyl 5-bromo-2-methylbenzoate 79669-50-4
49- 5-Chloro-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester 85174-68-1
50- 5-Bromo-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester
51- 5-Cyano-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester 3399-56-2
52- 5-Amino-1-(4-bromo-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester
53- 5-Chloro-1-p-tolyl-1H-pyrazole-3-carboxylic acid ethyl ester 460331-53-7
54- 5-Bromo-1-p-tolyl-1H-pyrazole-3-carboxylic acid ethyl ester 121434-51-3
55- 5-Amino-4-bromo-1-p-tolyl-1H-pyrazole-3-carboxylic acid ethyl ester
56- 5-Amino-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 70500-80-0
57- 5-Chloro-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 1172229-72-9
58- 5-Bromo-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
59- 5-Cyano-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
60- 5-Amino-4-bromo-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 1174305-82-8
61- ethyl 5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate 15001-08-8
62- ethyl 5-amino-1-(3-fluorophenyl)-1H-pyrazole-4-carboxylate 138907-70-7
63- ethyl 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate 91129-95-2
64- ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate 138907-68-3
65- ethyl 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate 14678-87-6
66- ethyl 5-amino-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate 16459-35-1
67- ethyl 5-amino-1-(2-bromophenyl)-1H-pyrazole-4-carboxylate 1019009-68-7
68- ethyl 5-amino-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylate 16459-33-9
69- ethyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-4-carboxylate 618070-65-8
70- ethyl 5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylate 138907-71-8
71- ethyl 1-(3-chlorophenyl)-5-fluoro-1H-pyrazole-4-carboxylate
72- ethyl 5-fluoro-1-(3-fluorophenyl)-1H-pyrazole-4-carboxylate
73- ethyl 5-fluoro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate
74- ethyl 5-fluoro-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate
75- ethyl 1-(4-chlorophenyl)-5-fluoro-1H-pyrazole-4-carboxylate
76- ethyl 5-fluoro-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate
77- ethyl 1-(2-bromophenyl)-5-fluoro-1H-pyrazole-4-carboxylate
78- ethyl 5-fluoro-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylate
79- ethyl 5-fluoro-1-(2-fluorophenyl)-1H-pyrazole-4-carboxylate
80- ethyl 1-(4-bromophenyl)-5-fluoro-1H-pyrazole-4-carboxylate
81- ethyl 5-chloro-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate
82- ethyl 5-chloro-1-(3-fluorophenyl)-1H-pyrazole-4-carboxylate
83- ethyl 5-chloro-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate 104909-40-2
84- ethyl 5-chloro-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate 288252-75-5
85- ethyl 5-chloro-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate 110821-36-8
86- ethyl 5-chloro-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate 110821-37-9
87- ethyl 1-(2-bromophenyl)-5-chloro-1H-pyrazole-4-carboxylate
88- ethyl 5-chloro-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylate 121716-35-6 98475-72-0
89- 110821-39-1 , 1082828-31-6 , 110821-40-4

90- ethyl 5-bromo-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate
ethyl 5-bromo-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylate
ethyl 1-(3-chlorophenyl)-5-cyano-1H-pyrazole-4-carboxylate 98476-16-5
ethyl 5-cyano-1-(3-fluorophenyl)-1H-pyrazole-4-carboxylate 98476-14-3
ethyl 5-cyano-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate
ethyl 5-cyano-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate 98476-22-3
ethyl 1-(4-chlorophenyl)-5-cyano-1H-pyrazole-4-carboxylate 98476-27-8
 
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