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Sure, I can make an assumption about the state of my local environment or parts of it (like a piece of metal), and that's well testable by observation. What's also testable in cosmology are the observations in my "space-time neighborhood", including the redshift of far-distant objects to determine the Hubble diagram with better and better accuracy (assuming of course certain laws on the luminosity of the objects to determine the distance). But here I just probe a very coarse grained classical picture of the universe, and that's sufficient to describe the observables. But this is far from having a description of the "state of the entire universe" and in fact not involving any quantum theory at all (it's just GR and a very crude model for the "matter" described as an ideal fluid). The same is true for the piece of metal, I can describe by some very coarse grained macroscopic (thermodynamic) observables like temperature.