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Difference Between GABA A and GABA B?

  1. Feb 29, 2012 #1
    Difference Between GABA A and GABA B?
  2. jcsd
  3. Feb 29, 2012 #2


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    Gold Member

    In what sense?

    At the molecular level, A receptors are Cl- ion channels, B receptors activate metabolic pathways. So A directly affects electrophysical properties, B affects molecular network dynamics through G protein cascades (which shut down the neuron's ion reactivity and down-regulates adenyl cyclase).
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