Difference Between GABA A and GABA B?

  1. Difference Between GABA A and GABA B?
     
  2. jcsd
  3. Pythagorean

    Pythagorean 4,622
    Gold Member

    In what sense?

    At the molecular level, A receptors are Cl- ion channels, B receptors activate metabolic pathways. So A directly affects electrophysical properties, B affects molecular network dynamics through G protein cascades (which shut down the neuron's ion reactivity and down-regulates adenyl cyclase).
     
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