When a cavitation bubble grows from a small nucleus to many times its original size, the collapse will begin at a maximum radius, RM, with a partial pressure of gas, pGM, which is very small indeed. In a typical cavitating flow RM is of the order of 100 times the original nuclei size, Ro. Consequently, if the original partial pressure of gas in the nucleus was about 1 bar the value of pGM at the start of collapse would be about 10-6 bar. If the typical pressure depression in the flow yields a value for (p∞*-p∞(0)) of, say, 0.1 bar it would follow from Equation 2.38 that the maximum pressure generated would be about 1010 bar and the maximum temperature would be 4×104 times the ambient temperature! Many factors, including the diffusion of gas from the liquid into the bubble and the effect of liquid compressibility, mitigate this result. Nevertheless, the calculation illustrates the potential for the generation of high pressures and temperatures during collapse and the potential for the generation of shock waves and noise.