Effects of gravity on blood pressure

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Discussion Overview

The discussion revolves around the effects of gravity on blood pressure and fluid dynamics, particularly in relation to how pressure differences influence blood flow in the human body and in theoretical models like U-shaped tubes. Participants explore concepts from cardiovascular physiology and fluid mechanics.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification
  • Debate/contested
  • Mathematical reasoning

Main Points Raised

  • One participant claims that blood pressure in the feet can rise to approximately 180 mmHg when standing, questioning how this is possible given that aortic pressure is 120 mmHg.
  • Another participant suggests that the initial claim of 180 mmHg may be too high but acknowledges that mechanisms such as lower chest pressure during breathing and one-way valves in veins assist in blood flow against gravity.
  • A different participant references a U-shaped tube model from a cardiovascular textbook, discussing how fluid can flow despite pressure differences, and seeks clarification on the implications for understanding blood flow in the human body.
  • One reply explains that in a static case, the pressure at the bottom of the U-shaped tube is influenced by both the weight of the fluid column and externally applied pressures, leading to fluid movement.
  • Another participant questions whether Poiseuille's equation applies in this context, suggesting that the equation might not hold due to the complexities introduced by gravitational effects.
  • A participant raises a question about whether a similar phenomenon to siphoning exists in the circulation of the inferior extremities, particularly regarding limitations due to cavitation.
  • One participant speculates that Bernoulli's equation accounts for kinetic and gravitational potential energy, noting inconsistencies in pressure comparisons across different points in the tube and considering frictional forces as a factor in maintaining pressure differences.

Areas of Agreement / Disagreement

Participants express varying views on the accuracy of pressure values and the applicability of different fluid dynamics equations. There is no consensus on the interpretations of the models discussed, and multiple competing perspectives remain throughout the conversation.

Contextual Notes

Participants highlight limitations in their understanding of fluid dynamics, particularly regarding assumptions in equations and the influence of gravitational forces. There are unresolved aspects concerning the application of Poiseuille's and Bernoulli's equations in the context of blood flow.

coolia
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When you stand up, blood pressure in your feet rise the most and become appx. 180 mmHg. How then does blood flow throughout the vascular when aortic pressure is 120 mmHg? difference in P=FlowX Resistance
 
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Hi coolia,

Sorry I missed this earlier. First, I think your 180 mmHg is a little too high, but you are correct that the pressure can often be greater than could be hydrostatically pulled up without some other mechanisms. There are two of which I am aware. First, due to breathing the pressure in the chest is, on average, about 5 mmHg lower than atmospheric. Second, the larger veins have valves in them that allow only one-way flow, when the leg muscles contract these valves help push the blood back up. Vericose veins are what result when these valves no longer function.
 
Ok, I agree with that in the circulatory system. However, I was reading Barnes and Levy Cardiovascular book and it shows a U-shaped rigid tube. The inflow pressure was 100 and the outflow was 0. The pressure at the bottom is greatest at appx. 130. Yet, fluid will still flow from one side of the tube to the other given the above conditions. If we use the equation delta P = Flow X Resistance. Delta P using the two ends of the U-shaped tube is 100-0 so fluid will flow in and come out. Yet, if we use delta P from the Top of the side of tube with the greater pressure and the bottom of the tube delta P will be 100-130=-30 based on this flow will be from bottom to top? I would like to know why this is the cause in this situation this will help me understand the human body better.
 
Ahh, I misunderstood your question. OK, that is fairly easy to answer.

Consider the bottom of the U at a moment when there is no flow. The weight of the column of fluid is equal to the weight of a 30 mm column of Hg, so the pressure due to the weight of the fluid is 30 mmHg. In addition there is the externally applied pressure of 100 mmHg on one side and 0 mmHg on the other side. So, in the static case, down at the bottom of the U there is a pressure of 130 mmHg on one side and 30 mmHg on the other side. Therefore the fluid at the bottom will begin to move (and similarly with the rest of the fluid).

Have you ever used a siphon? That is a similar concept, but in reverse.
 
So I'm assuming pouiselle's abreviated equation work does not hold for this case?, change in P= F x R.
 
is there a similar phenomenon in the reverse of a siphon (circulation of inferior extremity) where the maximum height of the siphon is limited due to cavitation?
 
I'm guessing the pouiselles equation doesn't take into consideration kinetic and gravitational potential energy. Bernoulli's equation does however. So constant, = v^2/2 +gh +P/p. gh will be higher at top, but at bottom will be turned into a greater P. v does not change throughout the tube because fluid is incompressible. What does not make sense with this however is if we compare the right side of the tube (P=0) to the left (P=100), gh will be the same, and so will the v term yet P will be different and so the constant is no longer constant. Help!

Oh yeah I forgot to take into consideration the frictional forces or resistance which is responsible for the loss of pressure on the left side, if we add that factor into the equation the constant will be a constant. I think I answered my own question, please tell me if this is the right logic. Thank you.
 

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